ArticleThe Journal of biological chemistry2018
Glycine
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Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
19.4field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 51 citations in OpenAlex.
- Sulfur amino acid restriction prevents S-adenosylmethionine-driven liver steatosis, hepatocellular carcinoma, and metabolic remodeling in high-fat-fed GNMT-null mice.bioRxiv : the preprint server for biology · 2026Article
- Role of methionine metabolism in cancer: recent advances in molecular mechanisms and therapeutic implications.Experimental hematology & oncology · 2026Review
- Glycine: The missing link between carbohydrate and xenobiotic metabolism in the maturing human hepatocyte.iScience · 2026Article
- Liver-Targeted AAV-DJ-hCBS Therapy Achieves Long-Term Correction of Metabolic Imbalance in CBS-Deficient Mice.International journal of molecular sciences · 2026Article
- The Hepatic Transcriptomes of Two Mouse Models of Liver Fibrosis Reveal Shared Molecular Patterns Associated with a Common Dysregulation of Folate Metabolism.The Journal of nutrition · 2026Article
- GNMT and Its Regulatory MicroRNAs as Biomarkers and Therapeutic Targets for Metabolic Dysfunction-Associated Fatty Liver Disease and Hepatocellular Carcinoma.International journal of molecular sciences · 2026Review
- The complex role of glycine N-methyltransferase in metabolism-a review.Molecular biology reports · 2025Review
- Review
- Transcriptional control of a metabolic switch regulating cellular methylation reactions is part of a common response to stress in divergent bee species.The Journal of experimental biology · 2024Article
- Exercise training adaptations in liver glycogen and glycerolipids require hepatic AMP-activated protein kinase in mice.American journal of physiology. Endocrinology and metabolism · 2024Article
- The Role of GNMT and MMP12 Expression in Determining TACE Efficacy: Validation at Transcription and Protein Levels.Journal of hepatocellular carcinoma · 2024Article
- Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice.American journal of physiology. Endocrinology and metabolism · 2023Article
- One Carbon Metabolism andLivers · 2022Article
- Metabolic reprogramming and epigenetic modifications on the path to cancer.Protein & cell · 2022Review
- Integrative metabolic flux analysis reveals an indispensable dimension of phenotypes.Current opinion in biotechnology · 2022Review
- Article
- Dysregulation of S-adenosylmethionine Metabolism in Nonalcoholic Steatohepatitis Leads to Polyamine Flux and Oxidative Stress.International journal of molecular sciences · 2022Article
- In vivoCurrent opinion in biotechnology · 2021Review
- Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation.Genome biology · 2021Article
- Serine, glycine and one‑carbon metabolism in cancer (Review).International journal of oncology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Curtis C HugheyFrom the Department of Molecular Physiology and Biophysics and curtis.hughey@vanderbilt.edu.
Elijah TreftsFrom the Department of Molecular Physiology and Biophysics and.
Deanna P BracyFrom the Department of Molecular Physiology and Biophysics and.
Freyja D JamesFrom the Department of Molecular Physiology and Biophysics and.
E Patrick DonahueFrom the Department of Molecular Physiology and Biophysics and.
David H WassermanFrom the Department of Molecular Physiology and Biophysics and.
Vanderbilt University · US
Funding
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MVanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MVanderbilt Mouse Metabolic Phenotyping CenterU2CDK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2016 to 2021
$6.3MINTEGRATED CONTROL OF MUSCLE GLUCOSE UPTAKE IN VIVOR01DK054902 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 1999 to 2020
$5.9MRole of the Cell Adhesome in Obesity-related Liver DiseasesR01DK050277 · NIDDK · VANDERBILT UNIVERSITY · PI MCGUINNESS, OWEN P · 1995 to 2023
$4.8MExercise and Fuel MetabolismR37DK050277 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2008 to 2017
$4.2MIntegrated Control of Muscle Glucose Uptake in VivoR56DK054902 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2009 to 2009
$388kNIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK050277NIDDK NIH HHS R01 DK054902NIDDK NIH HHS R37 DK050277NIDDK NIH HHS R56 DK054902NIDDK NIH HHS U24 DK059637NIDDK NIH HHS U2C DK059637
Abstract
Glycine
Indexed as
Gene DeletionGluconeogenesisAnimalsCarbonCitric Acid CycleEnergy MetabolismFatty LiverGlucoseGlycine N-MethyltransferaseLiverMaleMetabolic Flux AnalysisMethionineMiceMice, KnockoutS-AdenosylmethionineCarbonGlucoseGlycine N-MethyltransferaseGnmt protein, mouseMethionineS-Adenosylmethionineenergy metabolismgluconeogenesisintermediary metabolismisotopic tracerliver cancerliver metabolismliver steatosisliver steatosis and cancermetabolic flux analysisone-carbon metabolismpolyamineS-adenosylmethionine (SAM)stable isotopestransmethylationtranssulfuration
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.