Evidence map›Paper›PMID 29891414›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2018

Roux-en-Y gastric bypass is safe in elderly patients: a propensity-score matched analysis.

Taryn E Hassinger, J Hunter Mehaffey, Lily E Johnston, Robert B Hawkins, Bruce D Schirmer, Peter T Hallowell

Abstract read
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Taryn E HassingerDepartment of Surgery, University of Virginia, Charlottesville, Virginia. Electronic address: teh3rz@hscmail.mcc.virgina.edu.
J Hunter MehaffeyDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Lily E JohnstonDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Robert B HawkinsDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Bruce D SchirmerDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Peter T HallowellDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
University of Virginia · US

Funding

Cardiovascular Surgery Training ProgramT32HL007849 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI KRON, IRVING L., LAUBACH, VICTOR E · 1998 to 2025
$7.0M
Postdoctoral Training Grant for MDs in Surgical Oncology ResearchT32CA163177 · NCI · UNIVERSITY OF VIRGINIA · PI Craig Lee Slingluff, Allan Tsung · 2011 to 2026
$4.6M
NCI NIH HHS T32 CA163177NHLBI NIH HHS T32 HL007849
6 · The paper itself

Abstract

backgroundNumerous studies have established the effectiveness of Roux-en-Y gastric bypass (RYGB) for weight loss and co-morbidity amelioration. However, its safety and efficacy in elderly patients remains controversial.

objectivesTo evaluate outcomes in patients aged ≥60 years who underwent RYGB compared with nonsurgical controls with the hypothesis that RYGB provides weight loss benefits without differences in survival.

settingUniversity-affiliated tertiary center.

methodsAll patients who underwent RYGB from 1985 to 2015 were identified and divided into elderly (age ≥60) and nonelderly (age <60) groups. A nonsurgical elderly control population was identified using a clinical data repository of outpatient visits to propensity match elderly patients 4:1 on demographic characteristics, co-morbidities, and relevant preoperative substance/medication use. Unpaired appropriate univariate analyses compared each stratified group. Kaplan-Meier survival curves were fitted based on social security death data.

resultsA total of 2306 patients underwent RYGB. The 107 elderly patients had lower median body mass index (47.0 versus 49.9; P = .007) and higher rates of co-morbidities. Rates of complications did not differ between elderly and nonelderly patients. Elderly surgical patients were propensity matched 4:1 (10,044 controls) yielding 428 well-matched nonsurgical controls. The elderly group demonstrated significant percent reduction in excess body mass index compared with the control group (81.8% versus 10.3%; P < .001). Kaplan-Meier survival analysis with log-rank test demonstrated no difference in midterm survival (P = .63).

conclusionsA significant weight reduction benefit was identified after RYGB in elderly patients without a difference in midterm survival compared with propensity-matched controls, suggesting RYGB is a safe and efficacious weight loss strategy in the elderly.

Indexed as

Gastric BypassAdultComorbidityFemaleHumansKaplan-Meier EstimateMaleMiddle AgedObesity, MorbidPropensity ScoreWeight LossBariatricElderlyObesityRoux-en-Y gastric bypass (RYGB)Weight loss

Identifiers

PMID29891414
PMCPMC6153050
OpenAlexW2802911063

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.