ArticleDisability and health journal2018
Quality of life and psychological well-being in the early stages of multiple sclerosis (MS): Importance of adopting a biopsychosocial model.
Article in Disability and health journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- Neuroticism as a Common Factor in Depression and Anxiety Associated with Multiple Sclerosis-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- Prevalence and burden of multiple sclerosis-related fatigue: a systematic literature review.BMC neurology · 2021Pooled it
- Pooled it
- Peer support needs and engagement among people with multiple sclerosis: Associations with social support, loneliness and wellbeing: A cross-sectional study.Journal of health psychology · 2026Article
- The Role of Lifestyle Factors in Multiple Sclerosis: An Integrative Perspective.Brain sciences · 2026Review
- Quality of Life in Multiple Sclerosis Compared to Amyotrophic Lateral Sclerosis: Fatigue and Fast Disease Progression Interferes with the Ability to Psychosocially Adjust.Brain sciences · 2025Article
- Article
- The Relationship Between Perceived Social Support and Spiritual Well-Being in Patients With Multiple Sclerosis.Nursing open · 2025Article
- Article
- Fatigue management effects on social participation and environment management in individuals with multiple sclerosis: Quasi-experimental study.The British journal of occupational therapy · 2025Article
- Article
- Impact of Socio-Demographic Factors on Quality of Life and Coping Strategies of Children with Different Disabilities.Medicina (Kaunas, Lithuania) · 2024Article
- Determination of key hub genes in Leishmaniasis as potential factors in diagnosis and treatment based on a bioinformatics study.Scientific reports · 2024Article
- An Online Single-Session Cognitive Behavioral Therapy for Depression and Anxiety Associated with Multiple Sclerosis-Pilot Study.Behavioral sciences (Basel, Switzerland) · 2024Article
- Coping and psychological well-being among persons with relapsing-remitting multiple sclerosis: The role of perceived self-efficacy.Multiple sclerosis and related disorders · 2024Article
- Fostering quality of life in young adults living with multiple sclerosis: a pilot study of a co-created integrated intervention.Frontiers in psychology · 2024Article
- The Association of Health Locus of Control with Clinical and Psychosocial Aspects of Living with Multiple Sclerosis.Journal of clinical psychology in medical settings · 2023Article
- Social stigma and its relationship with quality of life in multiple sclerosis patients.BMC neurology · 2023Article
- Explaining the burden of psychosocial factors on the worsening symptoms of MS: a qualitative study of patients' experiences.BMC neurology · 2023Article
- Resilience, Stress, Well-Being, and Sleep Quality in Multiple Sclerosis.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
backgroundReductions in quality of life (QOL) exist among individuals with multiple sclerosis (MS).
objectiveThe present investigation aimed to adopt a biopsychosocial model in examining QOL in the early stages of MS.
methodsIndividuals with MS (34 with average to low QOL and 35 with high QOL) were compared on measures of disease symptoms, psychological functioning, personality, self-efficacy, locus of control (LOC), social support, and coping to determine the most salient predictors of QOL.
resultsIndividuals were matched on disease course and duration. Individuals with lower QOL reported more fatigue, sleep problems, pain, depression, and anxiety (d = 0.83-1.49, p's < 0.001). They also reported lower levels of self-efficacy, LOC, and social support (d = 0.75-1.50 p's < 0.01). They indicated higher levels of neuroticism (d = 1.31, p < .001) and lower levels of extraversion (d = 1.21, p < .001) and reported greater levels of disengagement as a means of coping (d = 0.75, p = .002). Those with high QOL endorsed more use of adaptive coping (d = 0.52 - 0.86, p's < 0.05). When taken together, LOC and anxiety were the most significant predictors, accounting for 40% of the variance.
conclusionEven early on in the illness, there exists differing levels of QOL. Identifying the psychological and social variables as well as the disease related factors is important, and in this case, may make a much greater contribution. Efforts to assure routine assessment and effective intervention aimed at these factors are warranted, particularly as an early intervention to assure maintenance/improvement in QOL among individuals with MS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.