Evidence map›Paper›PMID 29890960›Full record

ArticleBMC psychiatry2018

Symptom, alexithymia and self-image outcomes of Mentalisation-based treatment for borderline personality disorder: a naturalistic study.

J Löf, D Clinton, V Kaldo, G Rydén

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03295838 (Symptom, Alexithymia and Self-image Outcomes of Mentalization-Based Treatment for Borderline Personality Disorder), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03295838 nacompletednot on this map

Symptom, Alexithymia and Self-image Outcomes of Mentalization-Based Treatment for Borderline Personality Disorder: a Naturalistic Study

TypeinterventionalSponsorKarolinska InstitutetRan2007 to 2014Enrolled75ConditionsBorderline Personality DisorderArmsMentalization-based treatment
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  9. Misleading about MBT in Oslo.BMC psychiatry · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

J LöfStockholm Health Care Services, Stockholm County Council, Stockholm Psychiatry Southwest, Stockholm, Sweden.
D ClintonCenter for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Norra stationsgatan 69, 7 tr, 113 64, Stockholm, Sweden. david.clinton@ki.se.ORCID http://orcid.org/0000-0002-3536-6059
V KaldoStockholm Health Care Services, Stockholm County Council, Stockholm Psychiatry Southwest, Sweden, Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
G RydénChild and Adolescent Psychiatry Clinic, Stockholm, Sweden.
Stockholm County Council · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMentalisation-based treatment (MBT) in borderline personality disorder (BPD) has a growing evidence base, but there is a lack of effectiveness and moderator studies. The present study examined the effectiveness of MBT in a naturalistic setting and explored psychiatric and psychological moderators of outcome.

methodBorderline and general psychiatric symptoms, suicidality, self-harm, alexithymia and self-image were measured in a group of BPD patients (n = 75) receiving MBT; assessments were made at baseline, and subsequently after 6, 12 and 18 months (when treatment ended). Borderline symptoms were the primary outcome variable.

resultsBorderline symptoms improved significantly (d = 0.79, p < .001), as did general psychiatric symptoms, suicidality, self-harm, self-rated alexithymia and self-image. BPD severity or psychological moderators had no effect on outcome. Younger patients improved more on self-harm, although this could be explained by the fact that older patients had considerably lower baseline self-harm.

conclusionsMBT seems to be an effective treatment in a naturalistic setting for BPD patients. This study is one of the first studies of MBT showing that outcomes related to mentalisation, self-image and self-rated alexithymia improved. Initial symptom severity did not influence results indicating that MBT treatment is well adapted to patients with severe BPD symptoms.

trial registrationThe study was retrospectively registered 25 September 2017 in the ClinicalTrials.gov PRS registry, no. NCT03295838 .

Indexed as

MentalizationSelf ConceptSuicidal IdeationAdultAffective SymptomsBorderline Personality DisorderFemaleHumansMaleMiddle AgedPsychotherapyPsychotherapy, GroupRetrospective StudiesSelf-Injurious BehaviorTreatment OutcomeYoung AdultAlexithymiaBorderline personality disorderMentalization-based treatmentPragmatic clinical trials as topicPsychotherapyTreatment outcome

Identifiers

PMID29890960
PMCPMC5996479
OpenAlexW2808032078

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.