Evidence map›Paper›PMID 29890939›Full record

ArticleBMC genomics2018

A genome-wide scan for signatures of selection in Azeri and Khuzestani buffalo breeds.

Mahdi Mokhber, Mohammad Moradi-Shahrbabak, Mostafa Sadeghi, Hossein Moradi-Shahrbabak, Alessandra Stella, Ezequiel Nicolzzi, Javad Rahmaninia, John L Williams

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 69 citations in OpenAlex.

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  18. Frontiers in veterinary science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Mahdi MokhberDepartment of Animal Science, Faculty of Agriculture, Urmia University, 11Km Sero Road, P. O. Box: 165, Urmia, 5756151818, Iran. m.mokhber@urmia.ac.ir.
Mohammad Moradi-ShahrbabakDepartment of Animal Science, Faculty of Agricultural Science and Engineering, University College of Agriculture and Natural Resources (UTCAN), University of Tehran, P. O. Box: 4111, Karaj, 1417614418, Iran.
Mostafa SadeghiDepartment of Animal Science, Faculty of Agricultural Science and Engineering, University College of Agriculture and Natural Resources (UTCAN), University of Tehran, P. O. Box: 4111, Karaj, 1417614418, Iran.
Hossein Moradi-ShahrbabakDepartment of Animal Science, Faculty of Agricultural Science and Engineering, University College of Agriculture and Natural Resources (UTCAN), University of Tehran, P. O. Box: 4111, Karaj, 1417614418, Iran.
Alessandra StellaParco Tecnologico Padano (PTP), Via Einstein, Cascina Codazza, 26900, Lodi, Italy.
Ezequiel NicolzziParco Tecnologico Padano (PTP), Via Einstein, Cascina Codazza, 26900, Lodi, Italy.
Javad RahmaniniaDepartment of Animal Breeding and Genetics, Animal Science Research Institute of Iran (ASRI), Karaj, 3146618361, Iran.
John L WilliamsDavies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia.
University of Tehran · IRParco Tecnologico Padano · ITAgricultural Biotechnology Research Institute of Iran · IRUniversity of Adelaide · AUUrmia University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentification of genomic regions that have been targets of selection may shed light on the genetic history of livestock populations and help to identify variation controlling commercially important phenotypes. The Azeri and Kuzestani buffalos are the most common indigenous Iranian breeds which have been subjected to divergent selection and are well adapted to completely different regions. Examining the genetic structure of these populations may identify genomic regions associated with adaptation to the different environments and production goals.

resultsA set of 385 water buffalo samples from Azeri (N = 262) and Khuzestani (N = 123) breeds were genotyped using the Axiom® Buffalo Genotyping 90 K Array. The unbiased fixation index method (F

conclusionsCandidate genes identified in regions potentially under selection were associated with physiological pathways including milk production, cytoskeleton organization, growth, metabolic function, apoptosis and domestication-related changes include immune and nervous system development. The QTL identified are involved in economically important traits in buffalo related to milk composition, udder structure, somatic cell count, meat quality, and carcass and body weight.

Indexed as

Selection, GeneticAnimalsBuffaloesGenomeGenome-Wide Association StudyGenotypePolymorphism, Single NucleotideQuantitative Trait LociDivergent selectionGenetic structurePopulation differentiation index

Identifiers

PMID29890939
PMCPMC5996463
OpenAlexW2806635867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.