Evidence map›Paper›PMID 29890847›Full record

ArticleCell transplantation2018

Induced Pluripotent Stem Cells: A Powerful Neurodegenerative Disease Modeling Tool for Mechanism Study and Drug Discovery.

Chia-Yu Chang, Hsiao-Chien Ting, Ching-Ann Liu, Hong-Lin Su, Tzyy-Wen Chiou, Horng-Jyh Harn, Shinn-Zong Lin

Abstract read
In one paragraph

Article in Cell transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Harnessing Intelligence from Brain Cells In Vitro.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025
    Review
  3. Article
  4. Cellular models in autoinflammatory disease research.Clinical & translational immunology · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Cellular Models in Schizophrenia Research.International journal of molecular sciences · 2021
    Review
  10. Review
  11. Review
  12. Using induced pluripotent stem cell neuronal models to study neurodegenerative diseases.Biochimica et biophysica acta. Molecular basis of disease · 2020
    Review
  13. Article
  14. Cell transplantation
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chia-Yu ChangBio-innovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Hsiao-Chien TingBio-innovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Ching-Ann LiuBio-innovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Hong-Lin SuDepartment of Life Sciences, National Chung Hsing University, Taichung, Taiwan.
Tzyy-Wen ChiouDepartment of Life Science, National Dong Hwa University, Hualien, Taiwan.
Horng-Jyh HarnBio-innovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Shinn-Zong LinBio-innovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many neurodegenerative diseases are progressive, complex diseases without clear mechanisms or effective treatments. To study the mechanisms underlying these diseases and to develop treatment strategies, a reliable

Indexed as

disease modelingdrug screeninginduced pluripotent stem cells (iPSCs)mechanism studyNeurodegenerative diseaseneuronal differentiation

Identifiers

PMID29890847
PMCPMC6299199

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.