Evidence map›Paper›PMID 29890760›Full record

ArticleViruses2018

Genetic Characterization and Phylogenetic Analysis of Small Ruminant Lentiviruses Detected in Spanish Assaf Sheep with Different Mammary Lesions.

Elena Gayo, Vincenzo Cuteri, Laura Polledo, Giacomo Rossi, Juan F García Marín, Silvia Preziuso

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elena GayoPathological Anatomy Section, Animal Health Department, School of Veterinary Medicine, University of Leon, via Profesor Pedro Carmenes s/n Campus de Vegazana, 24071 León, Spain. egayr@unileon.es.
Vincenzo CuteriSchool of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy. vincenzo.cuteri@unicam.it.ORCID 0000-0001-9536-3506
Laura PolledoMicros Veterinaria, INDEGSAL, via Profesor Pedro Carmenes s/n Campus de Vegazana, 24071 León, Spain. laurapolledo@gmail.com.
Giacomo RossiSchool of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy. giacomo.rossi@unicam.it.
Juan F García MarínPathological Anatomy Section, Animal Health Department, School of Veterinary Medicine, University of Leon, via Profesor Pedro Carmenes s/n Campus de Vegazana, 24071 León, Spain. jfgarm@unileon.es.
Silvia PreziusoSchool of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy. silvia.preziuso@unicam.it.ORCID 0000-0001-5258-6742
Università di Camerino · ITUniversidad de León · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small Ruminant Lentiviruses (SRLVs) are widespread in many countries and cause economically relevant, slow, and persistent diseases in sheep and goats. Monitoring the genetic diversity of SRLVs is useful to improve the diagnostic tools used in the eradication programs. In this study, SRLVs detected in Spanish Assaf sheep with different grades of lymphoproliferative mastitis were sequenced. Genetic characterization showed that most samples belonged to type A and were closer to Spanish SRLV isolates previously classified as A2/A3. Four samples belonged to subtype B2 and showed higher homology with Italian B2 strains than with Spanish B2 isolates. Amino acid sequences of immuno-dominant epitopes in the gag region were very conserved while more alterations were found in the LTR sequences. No significant correlations were found between grades of mastitis and alterations in the sequences although samples with similar histological features were phylogenetically closer to each other. Broader genetic characterization surveys in samples with different grades of SRLV-lesions are required for evaluating potential correlations between SRLV sequences and the severity of diseases.

Indexed as

Genetic VariationAnimalsGenotypeLentivirusLentivirus InfectionsMammary Glands, AnimalPhylogenySequence Analysis, DNASequence HomologySheepSheep DiseasesSpaingenetic characterizationhistopathologysheepSmall Ruminant Lentivirusudder

Identifiers

PMID29890760
PMCPMC6024768
OpenAlexW2806720387

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.