Evidence map›Paper›PMID 29890756›Full record

ReviewInternational journal of molecular sciences2018

Protein Polymer-Based Nanoparticles: Fabrication and Medical Applications.

Kelsey DeFrates, Theodore Markiewicz, Pamela Gallo, Aaron Rack, Aubrie Weyhmiller, Brandon Jarmusik, Xiao Hu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 241 citations in OpenAlex.

  1. Review
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  7. Nanotherapy for Neural Retinal Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kelsey DeFratesDepartment of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA. defratesk6@students.rowan.edu.
Theodore MarkiewiczDepartment of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, USA. markiewit3@students.rowan.edu.
Pamela GalloDepartment of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA. gallop3@students.rowan.edu.
Aaron RackDepartment of Molecular and Cellular Biosciences, Rowan University, Glassboro, NJ 08028, USA. racka9@students.rowan.edu.
Aubrie WeyhmillerDepartment of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA. weyhmilla9@students.rowan.edu.
Brandon JarmusikDepartment of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA. jarmusikb1@students.rowan.edu.
Xiao HuDepartment of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA. hu@rowan.edu.ORCID 0000-0002-2579-2820
Rowan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticles are particles that range in size from about 1⁻1000 nanometers in diameter, about one thousand times smaller than the average cell in a human body. Their small size, flexible fabrication, and high surface-area-to-volume ratio make them ideal systems for drug delivery. Nanoparticles can be made from a variety of materials including metals, polysaccharides, and proteins. Biological protein-based nanoparticles such as silk, keratin, collagen, elastin, corn zein, and soy protein-based nanoparticles are advantageous in having biodegradability, bioavailability, and relatively low cost. Many protein nanoparticles are easy to process and can be modified to achieve desired specifications such as size, morphology, and weight. Protein nanoparticles are used in a variety of settings and are replacing many materials that are not biocompatible and have a negative impact on the environment. Here we attempt to review the literature pertaining to protein-based nanoparticles with a focus on their application in drug delivery and biomedical fields. Additional detail on governing nanoparticle parameters, specific protein nanoparticle applications, and fabrication methods are also provided.

Indexed as

Biomedical TechnologyDrug Delivery SystemsHumansNanoparticlesPolymersProteinsPolymersProteinsbioimagingbiomaterials fabricationdrug deliverynanomedicinenanoparticlesprotein

Identifiers

PMID29890756
PMCPMC6032199
OpenAlexW2807694747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.