Evidence map›Paper›PMID 29890669›Full record

ArticleMolecules (Basel, Switzerland)2018

Synthesis of 2-Mercapto-(2-Oxoindolin-3-Ylidene)Acetonitriles from 3-(4-Chloro-5

Boris Letribot, Régis Delatouche, Hervé Rouillard, Antoine Bonnet, Jean-René Chérouvrier, Lisianne Domon, Thierry Besson, Valérie Thiéry

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Boris LetribotUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. boris.letribot@gmail.com.
Régis DelatoucheUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. regis.delatouche@gmail.com.
Hervé RouillardUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. herve.rouillard@hotmail.com.
Antoine BonnetUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. antoine.bonnet@univ-lr.fr.
Jean-René ChérouvrierUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. jean-rene.cherouvrier@univ-lr.fr.
Lisianne DomonUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. lisianne.domon@univ-lr.fr.
Thierry BessonNormandie University, UNIROUEN, INSA Rouen, CNRS, COBRA UMR 6014, 76000 Rouen, France. thierry.besson@univ-rouen.fr.ORCID 0000-0003-3025-6659
Valérie ThiéryUniversity of La Rochelle, UMR CNRS 7266 LIENSs, 17000 La Rochelle, France. valerie.thiery@univ-lr.fr.ORCID 0000-0002-2096-0098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkylidene oxindoles are important functional moieties and building blocks in pharmaceutical and synthetic chemistry. Our interest in biologically active compounds focused our studies on the synthesis of novel oxindoles, bearing on the exocyclic double bond at the C8, CN, and S groups. Extending the potential applications of Appel’s salt, we developed a new synthetic approach by investigating the reactions of C5-substituted 2-oxindoles with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel’s salt) to give original (

Indexed as

AcetonitrilesCarbon-13 Magnetic Resonance SpectroscopyIndolesProton Magnetic Resonance SpectroscopySpectrometry, Mass, Electrospray IonizationAcetonitrilesIndoles1,2,3-dithiazole3-alkenyl-2-oxindoleAppel’s salt

Identifiers

PMID29890669
PMCPMC6100569

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.