Evidence map›Paper›PMID 29890662›Full record

ReviewMarine drugs2018

Exploring the Valuable Carotenoids for the Large-Scale Production by Marine Microorganisms.

Javier Torregrosa-Crespo, Zaida Montero, Juan Luis Fuentes, Manuel Reig García-Galbis, Inés Garbayo, Carlos Vílchez, Rosa María Martínez-Espinosa

Abstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Exploring the Potential ofMicroorganisms · 2025
    Review
  6. Article
  7. Article
  8. Microbial Bacterioruberin: A Comprehensive Review.Indian journal of microbiology · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Effects of Breeds on the Content of Functional Nutrition in Eggs.Animals : an open access journal from MDPI · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Javier Torregrosa-CrespoDepartment of Agrochemistry and Biochemistry, Biochemistry and Molecular Biology division, Faculty of Science, University of Alicante, Ap. 99, E-03080 Alicante, Spain. javitorregrosa@ua.es.
Zaida MonteroAlgal Biotechnology Group, University of Huelva, CIDERTA and Faculty of Science, Marine International Campus of Excellence (CEIMAR), Parque Huelva Empresarial S/N, 21007 Huelva, Spain. mariazaida.montero@hotmail.com.
Juan Luis FuentesAlgal Biotechnology Group, University of Huelva, CIDERTA and Faculty of Science, Marine International Campus of Excellence (CEIMAR), Parque Huelva Empresarial S/N, 21007 Huelva, Spain. juanlufc@gmail.com.
Manuel Reig García-GalbisDepartment of Nutrition and Dietetics, Faculty of Health Sciences, University of Atacama, Copayapu 2862, CP 1530000 Copiapó, Chile. manuel.reig@uda.cl.ORCID 0000-0002-4428-0652
Inés GarbayoAlgal Biotechnology Group, University of Huelva, CIDERTA and Faculty of Science, Marine International Campus of Excellence (CEIMAR), Parque Huelva Empresarial S/N, 21007 Huelva, Spain. garbayo@dqcm.uhu.es.
Carlos VílchezAlgal Biotechnology Group, University of Huelva, CIDERTA and Faculty of Science, Marine International Campus of Excellence (CEIMAR), Parque Huelva Empresarial S/N, 21007 Huelva, Spain. bital.uhu@gmail.com.ORCID 0000-0002-8164-1672
Rosa María Martínez-EspinosaDepartment of Agrochemistry and Biochemistry, Biochemistry and Molecular Biology division, Faculty of Science, University of Alicante, Ap. 99, E-03080 Alicante, Spain. rosa.martinez@ua.es.ORCID 0000-0003-2679-135X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids are among the most abundant natural pigments available in nature. These pigments have received considerable attention because of their biotechnological applications and, more importantly, due to their potential beneficial uses in human healthcare, food processing, pharmaceuticals and cosmetics. These bioactive compounds are in high demand throughout the world; Europe and the USA are the markets where the demand for carotenoids is the highest. The in vitro synthesis of carotenoids has sustained their large-scale production so far. However, the emerging modern standards for a healthy lifestyle and environment-friendly practices have given rise to a search for natural biocompounds as alternatives to synthetic ones. Therefore, nowadays, biomass (vegetables, fruits, yeast and microorganisms) is being used to obtain naturally-available carotenoids with high antioxidant capacity and strong color, on a large scale. This is an alternative to the in vitro synthesis of carotenoids, which is expensive and generates a large number of residues, and the compounds synthesized are sometimes not active biologically. In this context, marine biomass has recently emerged as a natural source for both common and uncommon valuable carotenoids. Besides, the cultivation of marine microorganisms, as well as the downstream processes, which are used to isolate the carotenoids from these microorganisms, offer several advantages over the other approaches that have been explored previously. This review summarizes the general properties of the most-abundant carotenoids produced by marine microorganisms, focusing on the genuine/rare carotenoids that exhibit interesting features useful for potential applications in biotechnology, pharmaceuticals, cosmetics and medicine.

Indexed as

Aquatic OrganismsBiomassBiotechnologyCarotenoidsDietary SupplementsHumansMicroalgaeCarotenoidsantioxidantsbioactive compoundsblue biotechnologycarotenoidsmarine microorganisms

Identifiers

PMID29890662
PMCPMC6025630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.