Evidence map›Paper›PMID 29890050›Full record

ArticlePhysiological reports2018

Diltiazem improves contractile properties of skeletal muscle in dysferlin-deficient BLAJ mice, but does not reduce contraction-induced muscle damage.

Morium Begam, Alyssa F Collier, Amber L Mueller, Renuka Roche, Sujay S Galen, Joseph A Roche

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Morium BegamPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan.
Alyssa F CollierProgram in Physical Therapy, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Amber L MuellerProgram in Molecular Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Renuka RocheEastern Michigan University School of Health Sciences, Ypsilanti, Michigan.
Sujay S GalenPhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan.
Joseph A RochePhysical Therapy Program, Department of Health Care Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan.ORCID 0000-0002-9497-6850
Eugene Applebaum College of Pharmacy and Health Sciences · USEastern Michigan University · USUniversity of Maryland, Baltimore · USWashington University in St. Louis · US

Funding

Rehabilitative Interventions for Rejuvenating the Regenerative Potential of Skeletal MuscleR03HD091648 · NICHD · WAYNE STATE UNIVERSITY · PI ROCHE, JOSEPH ANTONIO · 2017 to 2018
$154k
NICHD NIH HHS R03 HD091648
6 · The paper itself

Abstract

B6.A-Dysf

Indexed as

AnimalsCalcium Channel BlockersDiltiazemDisease Models, AnimalDysferlinMaleMice, KnockoutMuscle ContractionMuscle, SkeletalMuscular Dystrophies, Limb-GirdleCalcium Channel BlockersDiltiazemDysferlinDysf protein, mouseDiltiazemdysferlineccentric contractionsLGMD2BMiyoshi myopathymuscle damageskeletal muscle

Identifiers

PMID29890050
PMCPMC5995314
OpenAlexW2808211207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.