Evidence map›Paper›PMID 29889491›Full record

ReviewACS nano2018

Assessing and Mitigating the Hazard Potential of Two-Dimensional Materials.

Linda M Guiney, Xiang Wang, Tian Xia, André E Nel, Mark C Hersam

Abstract readReview
In one paragraph

Review in ACS nano, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Safety Assessment of Graphene-Based Materials.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Emerging 2D Nanomaterials for Biomedical Applications.Materials today (Kidlington, England) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Recent advances in bioelectronics chemistry.Chemical Society reviews · 2020
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda M Guiney
Xiang WangDivision of NanoMedicine, Department of Medicine, and California NanoSystems Institute , University of California , Los Angeles , California 90095 , United States.
Tian XiaDivision of NanoMedicine, Department of Medicine, and California NanoSystems Institute , University of California , Los Angeles , California 90095 , United States.ORCID 0000-0003-0123-1305
André E NelDivision of NanoMedicine, Department of Medicine, and California NanoSystems Institute , University of California , Los Angeles , California 90095 , United States.ORCID 0000-0002-5232-4686

Funding

Carbon Nanotube Structure-Activity Relationships for Predictive ToxicologyR01ES022698 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HERSAM, MARK C., NEL, ANDRE ELIAS · 2014 to 2018
$2.1M
NIEHS NIH HHS R01 ES022698
6 · The paper itself

Abstract

The family of two-dimensional (2D) materials is comprised of a continually expanding palette of unique compositions and properties with potential applications in electronics, optoelectronics, energy capture and storage, catalysis, and nanomedicine. To accelerate the implementation of 2D materials in widely disseminated technologies, human health and environmental implications need to be addressed. While extensive research has focused on assessing the toxicity and environmental fate of graphene and related carbon nanomaterials, the potential hazards of other 2D materials have only recently begun to be explored. Herein, the toxicity and environmental fate of postcarbon 2D materials, such as transition metal dichalcogenides, hexagonal boron nitride, and black phosphorus, are reviewed as a function of their preparation methods and surface functionalization. Specifically, we delineate how the hazard potential of 2D materials is directly related to structural parameters and physicochemical properties and how experimental design is critical to the accurate elucidation of the underlying toxicological mechanisms. Finally, a multidisciplinary approach for streamlining the hazard assessment of emerging 2D materials is outlined, thereby providing a pathway for accelerating their safe use in a range of technologically relevant contexts.

Indexed as

AnimalsBoron CompoundsEnvironmentHumansMetalsModels, MolecularNanostructuresNanotechnologyPhosphorusRisk AssessmentSurface PropertiesBoron Compoundsboron nitrideMetalsPhosphorus2D materialblack phosphorusenvironmental fatehexagonal boron nitridenanotoxicologyrisk assessmentsafetytoxicitytransition metal dichalcogenide

Identifiers

PMID29889491
PMCPMC6130817

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.