SynthesisThe British journal of radiology2018
Diffusion-weighted imaging for staging chronic kidney disease: a meta-analysis.
Synthesis in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The value of functional magnetic resonance imaging in the evaluation of diabetic kidney disease: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion.Artificial organs · 2026Article
- Multiparametric functional MRI for early detection of renal impairment: clinical applications and future directions.Abdominal radiology (New York) · 2026Review
- The role of texture analysis of T1 weighted images in diagnosis of chronic kidney disease.Scientific reports · 2026Article
- Delta corticomedullary apparent diffusion coefficient on MRI as a biomarker for prognosis in IgA nephropathy.Renal failure · 2025Article
- Article
- Multiparametric MRI: can we assess renal function differently?Clinical kidney journal · 2025Review
- Clinical Trial of Autologous Dendritic Cell Administration Effect on Water Molecule Diffusion and Anti-Inflammatory Biomarkers in Diabetic Kidney Disease.Current issues in molecular biology · 2024Article
- Ultrasound viscoelastic imaging in the noninvasive quantitative assessment of chronic kidney disease.Renal failure · 2024Article
- Diffusion-Weighted MRI in the Genitourinary System.Journal of clinical medicine · 2022Review
- Noninvasive assessment of kidney dysfunction in children by using blood oxygenation level-dependent MRI and intravoxel incoherent motion diffusion-weighted imaging.Insights into imaging · 2021Article
- Renal Diffusion-Weighted Imaging in Healthy Dogs: Reproducibility, Test-Retest Repeatability, and Selection of the Optimal b-value Combination.Frontiers in veterinary science · 2021Article
- Does diffusion-weighted magnetic resonance imaging help in the detection of renal parenchymal disease and staging/prognostication in chronic kidney disease?Polish journal of radiology · 2021Article
- Radiographic Imaging in Autosomal Dominant Polycystic Kidney Disease: A Claims Analysis.International journal of nephrology and renovascular disease · 2021Article
- ADC cut points for chronic kidney disease in pathologically-proven cholangiocarcinoma.European journal of radiology open · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective: To evaluate stages of chronic kidney disease (CKD) by apparent diffusion coefficient (ADC) obtained from diffusion weighted imaging (DWI) using a meta-analysis.
methods: Literature databases were searched from PubMed, Web of Science, Cochrane and Embase to identify relevant articles about DWI in CKD between 1999 and 2017. ADC values were extracted from the healthy group and CKD patients with different stages. Meta-analysis was conducted using STATA v. 12.0. A random-effects model was performed to acquire the effect estimate, which was expressed as a pooled weighted mean difference (WMD) with 95% confidence interval (CI). We performed comparisons of ADC values between the following groups: (1) the ADC values of the normal kidneys vs earlier Stage 1-2 of CKD; (2) Stage 3 vs the Stage 1-2 of CKD; (3) the Stage 4-5 vs the Stage 3.
results: Six studies were included in this meta-analysis. The CKD patients with earlier Stage 1-2 showed lower ADC values than the healthy subjects [WMD = -0.09, 95% CI(-0.12 to -0.06), p < 0.001]. However, no obvious difference in ADC values was found between the Stage 3 and Stage1-2 of CKD [WMD = -0.09, 95% CI (-0.18 to 0.01), p = 0.08]. The CKD Stage3 had higher ADC values than those of Stage4-5 [WMD = -0.21, 95% CI (-0.32 to -0.11), p = 0.01].
conclusion: DWI is an accurate and non-invasive imaging technique for early diagnosis and staging of CKD. Quantitative DWI may potentially play a role in making clinical decisions in the follow-up of CKD. ADVANCES IN KNOWLEDGE: DWI can be a valuable tool for staging of CKD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.