Evidence map›Paper›PMID 29888765›Full record

ArticleiScience2018

Cdc42 Regulates Neuronal Polarity during Cerebellar Axon Formation and Glial-Guided Migration.

Eve-Ellen Govek, Zhuhao Wu, Devrim Acehan, Henrik Molina, Keith Rivera, Xiaodong Zhu, Yin Fang, Marc Tessier-Lavigne, Mary Elizabeth Hatten

Open access · goldAbstract read
In one paragraph

Article in iScience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  5. Inhibition ofInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Coronin 2B Regulates Neuronal Migration via Rac1-Dependent Multipolar-Bipolar Transition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  10. Article
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  12. Improved post-stroke spontaneous recovery by astrocytic extracellular vesicles.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Article
  13. Article
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  15. Article
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  19. Article
  20. Tuba Activates Cdc42 during Neuronal Polarization Downstream of the Small GTPase Rab8a.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Eve-Ellen GovekLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065, USA.
Zhuhao WuLaboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Devrim AcehanThe Rockefeller University Electron Microscopy Resource Center, The Rockefeller University, New York, NY 10065, USA.
Henrik MolinaThe Rockefeller University Proteomics Resource Center, The Rockefeller University, New York, NY 10065, USA.
Keith RiveraMass Spectrometry Shared Resource, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Xiaodong ZhuLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065, USA.
Yin FangLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065, USA.
Marc Tessier-LavigneLaboratory of Brain Development and Repair, The Rockefeller University, New York, NY 10065, USA.
Mary Elizabeth HattenLaboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065, USA.
Rockefeller University · USCold Spring Harbor Laboratory · US

Funding

Role of mPar6 Polarity in CNS Neuronal MigrationR01NS051778 · NINDS · ROCKEFELLER UNIVERSITY · PI HATTEN, MARY ELIZABETH · 2006 to 2015
$3.7M
NINDS NIH HHS R01 NS051778
6 · The paper itself

Abstract

CNS cortical histogenesis depends on polarity signaling pathways that regulate cell adhesion and motility. Here we report that conditional deletion of the Rho GTPase

Identifiers

PMID29888765
PMCPMC5993048
OpenAlexW2789642699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.