Evidence map›Paper›PMID 29888339›Full record

ArticleOphthalmology. Retina2018

OCT Angiography Changes in the 3 Parafoveal Retinal Plexuses in Response to Hyperoxia.

Ahmed M Hagag, Alex D Pechauer, Liang Liu, Jie Wang, Miao Zhang, Yali Jia, David Huang

Abstract read
In one paragraph

Article in Ophthalmology. Retina, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 52 citations in OpenAlex.

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  14. Macular vessel density reduction in patients recovered from COVID-19: a longitudinal optical coherence tomography angiography study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ahmed M HagagCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Alex D PechauerCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Liang LiuCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Jie WangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Miao ZhangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Yali JiaCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
David HuangCasey Eye Institute, Oregon Health & Science University, Portland, Oregon.
Oregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
Functional and Structural Optical Coherence Tomography for GlaucomaR01EY023285 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2013 to 2026
$8.8M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
Wide-field and projection-resolved optical coherence tomography angiography in diabetic retinopathyR01EY027833 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HWANG, THOMAS, JIA, YALI · 2017 to 2020
$1.8M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY023285NEI NIH HHS R01 EY024544NEI NIH HHS R01 EY027833NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

purposeUse projection-resolved OCT angiography to investigate the autoregulatory response in the 3 parafoveal retinal plexuses under hyperoxia.

designProspective cohort study.

participantsNine eyes from 9 healthy participants.

methodsOne eye from each participant was scanned using a commercial spectral-domain OCT system. Two repeated macular scans (3 × 3 mm

main outcome measuresFlow index and vessel density were calculated from the en face angiograms of each of the 3 plexuses, as well as from the all-plexus inner retinal slab.

resultsHyperoxia induced significant reduction in the flow index (-11%) and vessel density (-7.8%) of only the deep capillary plexus (

conclusionsProjection-resolved OCT angiography was able to show that the retinal autoregulatory response to hyperoxia affects only the deep capillary plexus, but not the intermediate capillary plexus or superficial vascular complex.

Identifiers

PMID29888339
PMCPMC5991480
OpenAlexW2766724135

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.