ArticleTranslational vision science & technology2018
Macular Choroidal Thickening in Keratoconus Patients: Swept-Source Optical Coherence Tomography Study.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Pachymetric Thresholds for Keratoconus Progression Based on MS-39 Measurement Precision.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Corneal Higher-Order Aberrations and Posterior Segment Changes in Keratoconus: A Multimodal OCT and OCTA Study.Diagnostics (Basel, Switzerland) · 2026Article
- Evaluation of Microcirculation at the Optic Nerve Head in Eyes With Keratoconus.Investigative ophthalmology & visual science · 2026Article
- Staging of Keratoconus Indices Based on Localized Corneal Biomechanics Stress-Strain Index Map.Ophthalmology science · 2026Article
- Retinal thickness and vascular density changes in Keratoconus: A systematic review and meta-analysis.Heliyon · 2025Article
- Quantifying choroidal and retinal thicknesses variations via optical coherence tomography in different stages of pediatric keratoconus.BMC ophthalmology · 2024Article
- Retinal neurovascular assessment and choroidal vascularity index in patients with keratoconus.Scientific reports · 2024Article
- Relationship between Choroidal Thickness and Anterior Scleral Thickness in Patients with Keratoconus.Diagnostics (Basel, Switzerland) · 2024Article
- Subfoveal choroidal thickness increases after excimer laser-assisted penetrating keratoplasty but not after excimer laser-assisted deep anterior lamellar keratoplasty.Scientific reports · 2024Article
- Subfoveal and Parafoveal Choroidal Thickening in Patients with Keratoconus Using the ETDRS Grid on Swept-Source OCT.Ophthalmology and therapy · 2024Article
- Assessing progression limits in different grades of keratoconus from a novel perspective: precision of measurements of the corneal epithelium.Eye and vision (London, England) · 2024Article
- Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus.Scientific reports · 2023Article
- Choroidal thickness assessment in keratoconus patients treated with cross-linking compared to healthy population.International ophthalmology · 2023Observational
- Evaluation of Multimodal Biometric Parameters for Diagnosing Acute Angle Closure Secondary to Lens Subluxation.Ophthalmology and therapy · 2023Article
- Distribution of pediatric keratoconus by different age and gender groups.Frontiers in pediatrics · 2022Article
- Independent and interactive effects of eye rubbing and atopy on keratoconus.Frontiers in immunology · 2022Article
- The Role of Atopy in the Choroidal Profile of Keratoconus Patients.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Increased choroidal thickness is not a disease progression marker in keratoconus.Scientific reports · 2020Observational
- Posterior pole retinal thickness distribution pattern in keratoconus.International ophthalmology · 2020Article
- Choroidal thickness in keratoconus.International ophthalmology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the choroidal thickness (CT) profile in keratoconus (KC) patients using swept-source optical coherence tomography (SS-OCT).
methodsThis was a prospective, cross-sectional study. One hundred two eyes of 52 KC patients were studied using Pentacam and SS-OCT. The macular CT profile was created by manually measuring the distance between the retinal pigment epithelium and the choroid-sclera junction on horizontal b-scans at nine different macular locations. The results were compared to 93 eyes of 93 healthy controls.
resultsMean age of the KC group was 34.9 ± 13.5 years and mean axial length (AL) was 24.1 ± 1.3 mm. Mean topographic KC classification (TKC) was 2.0; 39 eyes were classified as early KC (TKC <1-2), 34 eyes as moderate (TKC 2, 2-3), and 29 as advanced (TKC 3+). Mean subfoveal CT was 383.2 μm in KC patients and 280.5 μm in control group (
conclusionsCT in KC patients is statistically thicker than in healthy population. After age 45, CT decreases approaching control group values. TRANSLATIONAL RELEVANCE: This study describes changes in the CT profile of KC patients, a disease that was considered purely corneal. These choroidal changes argue that KC is a disease that likely involves several ocular structures other than the cornea, and could open new research lines related to the pathophysiology of KC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.