Evidence map›Paper›PMID 29888070›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2018

NegBio: a high-performance tool for negation and uncertainty detection in radiology reports.

Yifan Peng, Xiaosong Wang, Le Lu, Mohammadhadi Bagheri, Ronald Summers, Zhiyong Lu

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

  1. Article
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  5. MetaChest: generalized few-shot learning of pathologies from chest X-rays.Visual computing for industry, biomedicine, and art · 2026
    Article
  6. Article
  7. A Large Language Model to Detect Negated Expressions in Radiology Reports.Journal of imaging informatics in medicine · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Enhancing Disease Detection in Radiology Reports Through Fine-tuning Lightweight LLM on Weak Labels.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025
    Article
  13. Article
  14. Article
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  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yifan PengNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Xiaosong WangDepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Le LuDepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Mohammadhadi BagheriDepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Ronald SummersDepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Zhiyong LuNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.

Funding

Named Entity Recognition and Relationship Extraction in BiomedicineZIALM091813 · NLM · NATIONAL LIBRARY OF MEDICINE · PI LU, ZHIYONG · 2013 to 2022
$13.4M
Computer Aided Detection for Radiologic ImagesZIACL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
6 · The paper itself

Abstract

Negative and uncertain medical findings are frequent in radiology reports, but discriminating them from positive findings remains challenging for information extraction. Here, we propose a new algorithm, NegBio, to detect negative and uncertain findings in radiology reports. Unlike previous rule-based methods, NegBio utilizes patterns on universal dependencies to identify the scope of triggers that are indicative of negation or uncertainty. We evaluated NegBio on four datasets, including two public benchmarking corpora of radiology reports, a new radiology corpus that we annotated for this work, and a public corpus of general clinical texts. Evaluation on these datasets demonstrates that NegBio is highly accurate for detecting negative and uncertain findings and compares favorably to a widely-used state-of-the-art system NegEx (an average of 9.5% improvement in precision and 5.1% in F1-score). AVAILABILITY: https://github.com/ncbi-nlp/NegBio.

Identifiers

PMID29888070
PMCPMC5961822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.