ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2018
Biopsy Records Do Not Reduce Diagnosis Variability in Cancer Patient EHRs: Are We More Uncertain After Knowing?
Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Machine learning approaches to predict early cardiac immune-related adverse events in patients receiving immune checkpoint inhibitors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- General Roadmap and Core Steps for the Development of AI Tools in Digital Pathology.Diagnostics (Basel, Switzerland) · 2022Article
- What Oncologists Want: Identifying Challenges and Preferences on Diagnosis Data Entry to Reduce EHR-Induced Burden and Improve Clinical Data Quality.JCO clinical cancer informatics · 2021Article
- Workflow Differences Affect Data Accuracy in Oncologic EHRs: A First Step Toward Detangling the Diagnosis Data Babel.JCO clinical cancer informatics · 2020Article
- Catch Me if You Can: Acute Events Hidden in Structured Chronic Disease Diagnosis Descriptions Show Detectable Recording Patterns in EHR.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Article
- Building Cancer Diagnosis Text to OncoTree Mapping Pipelines for Clinical Sequencing Data Integration and Curation.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020Article
- A tale of three subspecialties: Diagnosis recording patterns are internally consistent but Specialty-Dependent.JAMIA open · 2019Article
- Lost in Translation: Diagnosis Records Show More Inaccuracies After Biopsy in Oncology Care EHRs.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2019Article
- Exploring the Hazards of Scaling Up Clinical Data Analyses: A Drug Side Effect Discovery Case Report.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational ScienceArticle
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Authors and funding
5 authors.
Funding
Abstract
Diagnostic codes are crucial for analyses of electronic health record (EHR) data but their accuracy and precision are often lacking. Although providers enter precise diagnoses into progress notes, billing standards may limit the particularity of a diagnostic code. Variability also arises from the creation of multiple descriptions for a particular diagnostic code. We hypothesized that the variability of diagnostic codes would be greater before surgical pathology results were recorded in the medical record. A well annotated cohort of patients with brain neoplasms was studied. After diagnostic pathology reporting, the odds of more distinct diagnostic descriptions were 2.30 times higher (p=0.00358), entropy in diagnostic sequences was 2.26 times higher (p=0.0259) and entropy in diagnostic precision scores was 15.5 times higher (p=0.0324). Although diagnostic codes became more distinct on average after diagnostic pathology reporting, there was a paradoxical increase in the variability of the codes selected. Researchers must be aware of the inconsistencies and variability in particularity in structured diagnostic coding despite the presence of a definitive diagnosis.
Identifiers
29888044PMC5961789What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.