Evidence map›Paper›PMID 29887986›Full record

ArticleJournal of materials chemistry. B2014

Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design.

Charles H Jones, Anders P Hakansson, Blaine A Pfeifer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of materials chemistry. B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Charles H JonesDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260-4200, USA.
Anders P HakanssonDepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY 14260-4200, USA.
Blaine A PfeiferDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260-4200, USA.
University at Buffalo, State University of New York · US

Funding

Pneumococcal transition from nasopharyngeal biofilm carriage to otitis mediaR01DC013554 · NIDCD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CAMPAGNARI, ANTHONY A · 2014 to 2018
$1.7M
A Hybrid Biomaterial-biological Vector for Antigen Presenting Cell Gene DeliveryR03AI088485 · NIAID · TUFTS UNIVERSITY MEDFORD · PI PFEIFER, BLAINE A. · 2010 to 2011
$145k
NIAID NIH HHS R03 AI088485NIDCD NIH HHS R01 DC013554
6 · The paper itself

Abstract

The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and emerging strategies designed to elicit immune responses in the context of genetic vaccination. Selected strategies at the biomaterial-biological interface will be emphasized to illustrate the potential of coupling both fields towards a common goal.

Identifiers

PMID29887986
PMCPMC5990286
OpenAlexW2058708049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.