Evidence map›Paper›PMID 29887949›Full record

ArticleAmerican journal of translational research2018

S-allyl-cysteine attenuates carbon tetrachloride-induced liver fibrosis in rats by targeting STAT3/SMAD3 pathway.

Zhiqiang Gong, Huisheng Ye, Yu Huo, Lei Wang, Yanhong Huang, Min Huang, Xingxing Yuan

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Evidence-based complementary and alternative medicine : eCAM · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Gasotransmitters: Potential Therapeutic Molecules of Fibrotic Diseases.Oxidative medicine and cellular longevity · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zhiqiang GongFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Huisheng YeFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Yu HuoFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Lei WangFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Yanhong HuangFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Min HuangFaculty of Chinese Medicine Science, Guangxi University of Chinese Medicine Nanning 530222, Guangxi, China.
Xingxing YuanDepartment of Gastroenterology, Nangang Branch of Heilongjiang Academy of Traditional Chinese Medicine Harbin 150006, Heilongjiang, China.
Guangxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

S-allyl-cysteine (SAC) is one of the major compounds in aged garlic extract, and has been proved to be an endogenous donor of hydrogen sulfide (H

Indexed as

inflammationLiver fibrosisoxidationS-allyl-cysteineSMAD3TGFβ

Identifiers

PMID29887949
PMCPMC5992555
OpenAlexW2981782687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.