ReviewFrontiers in neurology2018
Accuracy of Rating Scales and Clinical Measures for Screening of Rapid Eye Movement Sleep Behavior Disorder and for Predicting Conversion to Parkinson's Disease and Other Synucleinopathies.
Review in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Longitudinal risk factors for developing depressive symptoms in Parkinson's disease.Journal of the neurological sciences · 2021Pooled it
- α-Synuclein aggregation and brain atrophy in SNCA-A53T transgenic monkeys are correlated with parkinsonism.Brain : a journal of neurology · 2026Article
- Neuromelanin-sensitive MRI for identifying dopamine transporter imaging abnormality risk in idiopathic rapid eye movement sleep behavior disorder.Brain imaging and behavior · 2026Article
- Brain-first versus body-first Parkinson's disease: Differential findings on pupillary, brainstem and vagus sonography.Journal of neurology · 2026Article
- Article
- Speech and Language Changes During Rapid Eye Movement (REM) Sleep with Potential Diagnostic Markers: A Systematic Review.Brain sciences · 2026Review
- Clinical validation study of the Persian version of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ-PER).Arquivos de neuro-psiquiatria · 2025Article
- Are We Asking the Right Questions? Sex Specificity of Dream Characteristics in Probable Rapid Eye Movement Sleep Behavior Disorder.Movement disorders clinical practice · 2025Article
- Genome-wide association study of REM sleep behavior disorder in Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Force control deficits in rapid eye movement behavior disorder and Parkinson's disease.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Differential striatal dopamine binding in Parkinson's Disease with and without REM sleep behavior disorder: A Tc-99 m TRODAT-1 SPECT study.GeroScience · 2025Article
- Clinical features, plasma neurotransmitter levels and plasma neurohormone levels among patients with early-stage Parkinson's disease with sleep disorders.Cell communication and signaling : CCS · 2025Article
- Slovak database of speech affected by neurodegenerative diseases.Scientific data · 2024Article
- Prevalence and characteristics of rapid eye movement sleep behaviour disorder in adults with migraine: a cross-sectional screening study.European journal of neurology · 2024Article
- Differentiating Prodromal Dementia with Lewy Bodies from Prodromal Alzheimer's Disease: A Pragmatic Review for Clinicians.Neurology and therapy · 2024Article
- Risk stratification for phenoconversion in patients with isolated REM sleep behavior disorder. A follow-up study from Turkey.Revista de neurologia · 2024Article
- Functional and free-water imaging in rapid eye movement behaviour disorder and Parkinson's disease.Brain communications · 2024Article
- The Genetic Basis of Probable REM Sleep Behavior Disorder in Parkinson's Disease.Brain sciences · 2023Article
- Inaccurate self-report of olfactory dysfunction in REM Sleep Behaviour Disorder and implications for prognosis.Clinical parkinsonism & related disorders · 2023Article
- Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects.Nature communications · 2022Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by repeated episodes of REM sleep-related vocalizations and/or complex motor behaviors. Definite diagnosis of RBD is based on history and polysomnography, both of which are less accessible due to the lack of trained specialists and high cost. While RBD may be associated with disorders like narcolepsy, focal brain lesions, and encephalitis, idiopathic RBD (iRBD) may convert to Parkinson's disease (PD) and other synucleinopathies in more than 80% of patients and it is to date the most specific clinical prodromal marker of PD. Identification of individuals at high risk for development of PD is becoming one of the most important topics for current PD-related research as well as for future treatment trials targeting prodromal PD. Furthermore, concomitant clinical symptoms, such as subtle motor impairment, hyposmia, autonomic dysfunction, or cognitive difficulties, in subjects with iRBD may herald its phenoconversion to clinically manifest parkinsonism. The assessment of these motor and non-motor symptoms in iRBD may increase the sensitivity and specificity in identifying prodromal PD subjects. This review evaluates the diagnostic accuracy of individual rating scales and validated single items for screening of RBD and the role and accuracy of available clinical, electrophysiological, imaging, and tissue biomarkers in predicting the phenoconversion from iRBD to clinically manifest synucleinopathies.
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