Observational studyJournal of perinatology : official journal of the California Perinatal Association2018
Early diastolic dysfunction and respiratory morbidity in premature infants: an observational study.
Observational study in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Neonatal acute kidney injury and the patent ductus arteriosus.Pediatric nephrology (Berlin, Germany) · 2026Review
- Caring for the smallest hearts: cardiovascular phenotypes and assessment in tiny babies.Pediatric research · 2026Review
- Evaluation of Biventricular Diastolic Function in Preterm Infants in the First Week of Postnatal Life.Pediatric cardiology · 2026Observational
- [Selective interpretation of the "Guidelines and recommendations for targeted neonatal echocardiography and cardiac point-of-care ultrasound in the neonatal intensive care unit: an update from the American Society of Echocardiography"].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Article
- Early targeted neonatal echocardiography identifies biventricular dysfunction and pulmonary hypertension associated with death or severe bronchopulmonary dysplasia in infants born before 29 weeks' gestation.Frontiers in pediatrics · 2026Article
- Extremely preterm infants with adverse neurological outcome present more frequently impaired right ventricular performance.Pediatric research · 2025Observational
- Article
- Prophylactic indomethacin and the risk of serious pulmonary hemorrhages in preterm infants less than 28 weeks' gestation.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Monitoring and evaluation of hypotension in the extremely preterm.Frontiers in cardiovascular medicine · 2024Review
- The association between patterns of early respiratory disease and diastolic dysfunction in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Patent ductus arteriosus, bronchopulmonary dysplasia and pulmonary hypertension-a complex conundrum with many phenotypes?Pediatric research · 2023Article
- Exercise Training Improves Exercise Capacity in Preterm-Born Adults: Lessons for Clinical Trials?American journal of respiratory and critical care medicine · 2023Article
- Left Ventricular Diastolic Function in Subjects Conceived through Assisted Reproductive Technologies.Journal of clinical medicine · 2022Article
- Understanding the preterm human heart: What do we know so far?Anatomical record (Hoboken, N.J. : 2007) · 2022Review
- Prematurity and Pulmonary Vein Stenosis: The Role of Parenchymal Lung Disease and Pulmonary Vascular Disease.Children (Basel, Switzerland) · 2022Review
- Percutaneous Closure of Patent Ductus Arteriosus.Clinics in perinatology · 2022Review
- Safety, Feasibility, and Impact of Enalapril on Cardiorespiratory Physiology and Health in Preterm Infants with Systemic Hypertension and Left Ventricular Diastolic Dysfunction.Journal of clinical medicine · 2021Article
- Primary pulmonary vein stenosis during infancy: state of the art review.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Left Ventricle Phenotyping Utilizing Tissue Doppler Imaging in Premature Infants with Varying Severity of Bronchopulmonary Dysplasia.Journal of clinical medicine · 2021Article
- Left Ventricular Diastolic Dysfunction and Diastolic Heart Failure in Preterm Infants.Pediatric cardiology · 2019Observational
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test if diastolic dysfunction measured on day one of age is associated with the need for invasive ventilation in preterm infants. STUDY
designWe conducted a retrospective observational tissue Doppler echocardiographic study over the first 12 h of age for infants born <32 weeks who were invasively ventilated, and infants on continuous positive pressure ventilation (CPAP).
resultsOne hundred and eighty-three infants were included (27 ± 2 weeks and 999 ± 296 g). Invasively ventilated infants [(n = 96 (53%)] had lower left ventricular (LV) e' (3.4 ± 1.0 vs. 4.1 ± 1.5 cm/s, p < 0.01) and lower LV ea' ratio (0.8 ± 0.2 vs. 1.0 ± 0.4, p < 0.01), even after adjusting for common neonatal confounders (LV e' adjusted OR 0.62, 95% CI 0.45 - 0.87, p < 0.01; LV ea' adjusted OR 0.14, 95% CI 0.03-0.68, p = 0.01).
conclusionLV diastolic dysfunction is independently associated with a higher risk for invasive ventilation on day one of age.
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