Evidence map›Paper›PMID 29887605›Full record

GuidelineEye (London, England)2018

The Royal College of Ophthalmologists recommendations on screening for hydroxychloroquine and chloroquine users in the United Kingdom: executive summary.

Imran H Yusuf, Barny Foot, James Galloway, Michael R Ardern-Jones, Sarah-Lucie Watson, Cathy Yelf, Michael A Burdon, Paul N Bishop, Andrew J Lotery

Registry-linked trialAbstract readPractice GuidelineReview
In one paragraph

Guideline in Eye (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04394416 (Randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults With COVID-19), which is not on this map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04394416 phase3terminatednot on this mapstarted 2020, after this paper: background citation

Randomized Double-Blind Placebo-Controlled Trial on the Safety and Efficacy of Imatinib for Hospitalized Adults With COVID-19

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan2020 to 2025Enrolled21ConditionsCOVID-19ArmsImatinib, Placebo oral tablet
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. Guideline
  4. Article
  5. Progression of hydroxychloroquine-induced retinopathy after drug cessation.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Observational
  6. Article
  7. Review
  8. Observational
  9. Hydroxychloroquine monotherapy in sarcoidosis: Indications, efficacy, and side effects.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  10. Factors associated with early hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Hydroxychloroquine-induced Retinal Toxicity.Frontiers in pharmacology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Imran H YusufOxford Eye Hospital, West Wing, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK.
Barny FootThe Royal College of Ophthalmologists, 18 Stephenson Way, Kings Cross, London, NW1 2HD, UK.
James GallowayDepartment of Rheumatology, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
Michael R Ardern-JonesDepartment of Dermatology, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, Hampshire, SO16 6YD, UK.
Sarah-Lucie WatsonRoyal Berkshire Hospital, London Road, Reading, Berkshire, RG1 5AN, UK.
Cathy YelfThe Macular Society, Crown Chambers, South St, Andover, Hampshire, SP10 2BN, UK.
Michael A BurdonQueen Elizabeth Hospital, Mindelsohn Way, Edgbaston, Birmingham, B15 2GW, UK.
Paul N BishopManchester Royal Eye Hospital, Manchester University Hospitals NHS Foundation Trust, Manchester, M13 9WL & School of Biological Sciences, University of Manchester, Manchester, M13 9PL, UK.
Andrew J LoteryClinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, SO16 6YD, UK. A.J.Lotery@soton.ac.uk.ORCID http://orcid.org/0000-0001-5541-4305

Funding

Medical Research Council MR/R000735/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diagnostic Techniques, OphthalmologicalChloroquineClinical ProtocolsHumansHydroxychloroquineMass ScreeningRetinal DiseasesUnited KingdomChloroquineHydroxychloroquine

Identifiers

PMID29887605
PMCPMC6043500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.