ArticleInternational journal of cardiology2018
Relationship between QRS duration and incident atrial fibrillation.
Article in International journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Risk of Atrial Fibrillation Following Left Bundle Branch Area Pacing versus Right Ventricular Pacing and Biventricular Pacing: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Electrocardiographic Predictors of Atrial Fibrillation.Medical sciences (Basel, Switzerland) · 2023Pooled it
- Electrophysiological characterization of pre-adolescents born with intrauterine growth restriction: insights from clinical and computational data.The Journal of physiology · 2026Article
- Risk factors of atrial fibrillation progression in patients with congenital heart disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- From Minor Monitoring to Major Insight: Predicting AF Development in the Congenital Heart Disease Population.Journal of cardiovascular development and disease · 2026Article
- Article
- Screening Tool for Paroxysmal Atrial Fibrillation Based on a Deep-Learning Algorithm Using Printed 12-Lead Electrocardiographic Records during Sinus Rhythm.Reviews in cardiovascular medicine · 2024Article
- QTc interval prolongation and risk of atrial fibrillation recurrence: a meta-analysis and observational cohort study.Frontiers in cardiovascular medicine · 2024Article
- Evaluation of QRS duration and presence of fragmented QRS in patients with inflammatory bowel disease.International journal of medical sciences · 2024Article
- Electrocardiographic parameters and the risk of new-onset atrial fibrillation in the general population: the Rotterdam Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Clinical applicability of an artificial intelligence prediction algorithm for early prediction of non-persistent atrial fibrillation.Frontiers in cardiovascular medicine · 2023Article
- Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.Nature communications · 2022Article
- Combined Effects of Age and Comorbidities on Electrocardiographic Parameters in a Large Non-Selected Population.Journal of clinical medicine · 2022Article
- Electrocardiographic QRS duration is influenced by body mass index and sex.International journal of cardiology. Heart & vasculature · 2021Article
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8 authors at 5 institutions in 5 countries.
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Abstract
backgroundQRS duration (QRSd), a measure of ventricular conduction, has been associated with adverse cardiovascular outcomes, but its relationship with incident atrial fibrillation (AF) is poorly understood. METHODS AND
resultsThis study included 15,314 participants from the Atherosclerosis Risk in Communities (ARIC) study who were free of AF at baseline. QRSd was automatically measured from resting 12-lead electrocardiograms (ECGs) at baseline. Incident AF cases were systematically ascertained using ECGs, hospital discharge diagnoses and death certificates. Multivariable adjusted Cox regression analyses were performed to investigate the relationship between QRSd and incident AF. Mean age of our population was 54 ± 6 years (55% females). During a median follow-up of 21.2 years, 2041 confirmed incident AF cases occurred. In multivariable adjusted Cox models, a 1-SD increase in QRSd was associated with a hazard ratio (HR) (95% CI) for AF of 1.05 (1.01; 1.10), p = 0.01. This relationship was significant among women (HR per 1-SD increase in QRSd (95% CI) 1.13 (1.06; 1.20), p < 0.001), but not among men (1.00 (0.95; 1.06), p = 0.97) (p for interaction 0.005). Compared to individuals with a QRSd <100 ms, the HRs for incident AF in individuals with a QRSd of 100-119 and ≥120 ms were 1.13 (1.02; 1.26) and 1.35 (1.08; 1.68), respectively (p for trend 0.002). Again, this relationship was significant among women (p for trend <0.001) but not among men (p for trend 0.23).
conclusionIn this large population-based study, QRSd was an independent predictor of incident AF among women, but not in men. Further studies are needed to better understand the underlying mechanisms.
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