Evidence map›Paper›PMID 29886566›Full record

ReviewCurrent gastroenterology reports2018

Mucosal Impedance: a New Approach to Diagnosing Gastroesophageal Reflux Disease and Eosinophilic Esophagitis.

Caroline Barrett, Yash Choksi, Michael F Vaezi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Guideline
  2. Novel Technique to Diagnose Gastroesophageal Reflux Disease.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  3. Article
  4. Article
  5. A novelVeterinary world · 2020
    Article
  6. New Developments in the Diagnosis and Management of Gastroesophageal Reflux.Current treatment options in gastroenterology · 2020
    Review
  7. Why differences between New York and New Delhi matter in approach to gastroesophageal reflux disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Article
  8. Advances in the Diagnosis and Treatment of GERD: New Tricks for an Old Disease.Current treatment options in gastroenterology · 2019
    Review
  9. New Developments in Esophageal Motility Testing.Current treatment options in gastroenterology · 2019
    Review
  10. New Developments in the Diagnosis and Treatment of Eosinophilic Esophagitis.Current treatment options in gastroenterology · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caroline BarrettDivision of Gastroenterology, Hepatology and Nutrition, Vanderbilt Medical Center, 1660 TVC, 1301 -22nd Ave. South, Nashville, TN, 37232-5280, USA.
Yash ChoksiDivision of Gastroenterology, Hepatology and Nutrition, Vanderbilt Medical Center, 1660 TVC, 1301 -22nd Ave. South, Nashville, TN, 37232-5280, USA.
Michael F VaeziDivision of Gastroenterology, Hepatology and Nutrition, Vanderbilt Medical Center, 1660 TVC, 1301 -22nd Ave. South, Nashville, TN, 37232-5280, USA. Michael.vaezi@vanderbilt.edu.
Vanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn this review, we discuss current diagnostic testing modalities for both gastroesophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) and then introduce mucosal impedance (MI), a novel technology that measures epithelial integrity in real time during endoscopy. We describe the advantages and disadvantages of MI as compared with traditional diagnostic testing. RECENT

findingsWe review studies that demonstrate that GERD and EoE have distinct MI patterns, and that physicians can accurately diagnose and distinguish the two during endoscopy with minimal time added to the procedure. We also review studies showing that MI has the capability to assess treatment response in both GERD and EoE and that it can be used to diagnose GERD in patients with extraesophageal reflux symptoms. Mucosal impedance testing is a major advancement in the diagnosis of GERD and EoE. Future studies are planned to assess whether MI can be used as a treatment endpoint in EoE and whether it can be used to predict response to anti-reflux surgery.

Indexed as

Diagnostic Techniques, Digestive SystemElectric ImpedanceEosinophilic EsophagitisEsophagoscopyGastroesophageal RefluxHumansMucous MembraneEosinophilic esophagitisGastroesophageal reflux diseaseMucosal impedance

Identifiers

PMID29886566
OpenAlexW2807228369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.