Evidence map›Paper›PMID 29886421›Full record

ArticleJournal of the American Heart Association2018

Prognostic Utility of Soluble TREM-1 in Predicting Mortality and Cardiovascular Events in Patients With Acute Myocardial Infarction.

Yun Kai Wang, Jia Ni Tang, Yun Li Shen, Bo Hu, Chun Yu Zhang, Ming Hui Li, Rui Zhen Chen, Jun Bo Ge, Xue Bo Liu

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yun Kai WangDepartment of Cardiology, Shanghai East Hospital, Tongji University, Shanghai, China liuxuebo70@126.com cloudopen002@126.com.
Jia Ni TangDepartment of Cardiology, Tongji Hospital, Tongji University, Shanghai, China.
Yun Li ShenDepartment of Cardiology, Shanghai East Hospital, Tongji University, Shanghai, China.
Bo HuDepartment of Cardiology, Shanghai East Hospital, Tongji University, Shanghai, China.
Chun Yu ZhangDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ming Hui LiDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Rui Zhen ChenDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Jun Bo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xue Bo LiuDepartment of Cardiology, Tongji Hospital, Tongji University, Shanghai, China liuxuebo70@126.com cloudopen002@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriggering receptor expressed on myeloid cells-1 (TREM-1) is thought to be critical for inflammatory signal amplification and involved in the development of atherosclerosis. TREM-1 is significantly increased in patients with myocardial infarction. The aim of this study was to investigate the association between soluble TREM-1 (sTREM-1) and mortality and cardiovascular events in patients with acute myocardial infarction. METHODS AND

resultsWe included 838 consecutive patients with acute myocardial infarction from October 7, 2012 to December 5, 2014. Blood samples were collected from patients with acute myocardial infarction immediately after diagnosis. During follow-up, 88 patients died, and 180 patients reached the combined end points of major adverse cardiovascular event (MACE). Patients with high sTREM-1 (higher than the median) had increased risk of all-cause mortality and MACE compared with those with low sTREM-1 (log-rank test,

conclusionssTREM-1 was significantly associated with all-cause mortality and MACE, independent of established conventional risk factors in patients with acute myocardial infarction.

Indexed as

AgedBiomarkersCase-Control StudiesCause of DeathC-Reactive ProteinFemaleHumansMaleMiddle AgedNon-ST Elevated Myocardial InfarctionPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsST Elevation Myocardial InfarctionBiomarkersC-Reactive ProteinTREM1 protein, humanTriggering Receptor Expressed on Myeloid Cells-1acute myocardial infarctionall‐cause mortalitymajor adverse cardiac eventprognosistriggering receptor expressed on myeloid cells‐1

Identifiers

PMID29886421
PMCPMC6220534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.