Evidence map›Paper›PMID 29886187›Full record

ReviewTicks and tick-borne diseases2018

The Tick Cell Biobank: A global resource for in vitro research on ticks, other arthropods and the pathogens they transmit.

Lesley Bell-Sakyi, Alistair Darby, Matthew Baylis, Benjamin L Makepeace

Open access · hybridAbstract readReview
In one paragraph

Review in Ticks and tick-borne diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
11.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  7. Cultivation ofJournal of veterinary research · 2025
    Article
  8. Article
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  10. Propagation dynamics of Anaplasma marginale in a Brazilian tick cell line (RBME-6) derived from Rhipicephalus microplus.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025
    Article
  11. Article
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  13. Article
  14. Article
  15. Article
  16. Frontiers in cellular and infection microbiology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lesley Bell-SakyiInstitute of Infection and Global Health, University of Liverpool, Liverpool Science Park IC2, 146 Brownlow Hill, Liverpool L3 5RF, United Kingdom. Electronic address: L.Bell-Sakyi@liverpool.ac.uk.
Alistair DarbyInstitute of Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool L69 7ZB, United Kingdom. Electronic address: Alistair.Darby@liverpool.ac.uk.
Matthew BaylisInstitute of Infection and Global Health, University of Liverpool, Liverpool Science Park IC2, 146 Brownlow Hill, Liverpool L3 5RF, United Kingdom; NIHR Health Protection Research Institute in Emerging and Zoonotic Infections, Institute of Infection and Global Health, University of Liverpool, The Ronald Ross Building, 8 West Derby Street, Liverpool L69 7BE, United Kingdom. Electronic address: matthew.baylis@liverpool.ac.uk.
Benjamin L MakepeaceInstitute of Infection and Global Health, University of Liverpool, Liverpool Science Park IC2, 146 Brownlow Hill, Liverpool L3 5RF, United Kingdom. Electronic address: blm1@liverpool.ac.uk.
University of Liverpool · GB

Funding

Biotechnology and Biological Sciences Research Council BB/P024270/1Biotechnology and Biological Sciences Research Council BB/P024378/1
6 · The paper itself

Abstract

Tick cell lines are increasingly used in many fields of tick and tick-borne disease research. The Tick Cell Biobank was established in 2009 to facilitate the development and uptake of these unique and valuable resources. As well as serving as a repository for existing and new ixodid and argasid tick cell lines, the Tick Cell Biobank supplies cell lines and training in their maintenance to scientists worldwide and generates novel cultures from tick species not already represented in the collection. Now part of the Institute of Infection and Global Health at the University of Liverpool, the Tick Cell Biobank has embarked on a new phase of activity particularly targeted at research on problems caused by ticks, other arthropods and the diseases they transmit in less-developed, lower- and middle-income countries. We are carrying out genotypic and phenotypic characterisation of selected cell lines derived from tropical tick species. We continue to expand the culture collection, currently comprising 63 cell lines derived from 18 ixodid and argasid tick species and one each from the sand fly Lutzomyia longipalpis and the biting midge Culicoides sonorensis, and are actively engaging with collaborators to obtain starting material for primary cell cultures from other midge species, mites, tsetse flies and bees. Outposts of the Tick Cell Biobank will be set up in Malaysia, Kenya and Brazil to facilitate uptake and exploitation of cell lines and associated training by scientists in these and neighbouring countries. Thus the Tick Cell Biobank will continue to underpin many areas of global research into biology and control of ticks, other arthropods and vector-borne viral, bacterial and protozoan pathogens.

Indexed as

Biological Specimen BanksIn Vitro TechniquesResearchAnimalsArachnid VectorsArthropodsCell LineDisease VectorsMitesPsychodidaeResearch DesignTick-Borne DiseasesTicksArthropodIntracellular bacteriaMidgeMiteSand flyTick cell line

Identifiers

PMID29886187
PMCPMC6052676
OpenAlexW2807616962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.