ArticleJACC. Heart failure2018
Comparing Measures to Assess Health-Related Quality of Life in Heart Failure With Preserved Ejection Fraction.
Article in JACC. Heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04327596 (Randomized Clinical Trial of Radiofrequency Ablation for Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction for Reduced Healthcare Utilization), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Clinical Trial of Radiofrequency Ablation for Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction for Reduced Healthcare Utilization
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Assessment of patient-reported outcomes measures in heart failure: a systematic review.Heart failure reviews · 2024Pooled it
- Extended-Release Oral Milrinone for the Treatment of Heart Failure With Preserved Ejection Fraction.Journal of the American Heart Association · 2020Trial
- Clinical Impact of Digital Health Interventions with Educational Components for Patients with Heart Failure: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Comprehensive Individualized nursing intervention enhances health outcomes and quality of life in patients with heart failure.BMC cardiovascular disorders · 2026Article
- Effects of standing Baduanjin exercise on cardiac function and quality of life in patients with chronic heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Review
- Review
- Measuring Patient-Reported Outcomes in Ischemic Heart Disease: Validation of the Greek HeartQoL Questionnaire.American journal of medicine open · 2025Article
- Baseline Patient-Reported Health Status Predicts Hospitalization Duration and Cost in Chronic Heart Failure.Cureus · 2025Article
- Assessment of the Physical and Emotional Health-Related Quality of Life Among Congestive Heart Failure Patients with Preserved and Reduced Ejection Fraction at a Quaternary Care Teaching Hospital in Coastal Karnataka in India.Healthcare (Basel, Switzerland) · 2025Article
- A composite measurement concept for monitoring cardiac function in Fabry disease.Orphanet journal of rare diseases · 2025Article
- Quality of life in heart failure. The heart of the matter. A scientific statement of the Heart Failure Association and the European Association of Preventive Cardiology of the European Society of Cardiology.European journal of heart failure · 2025Article
- The Role of Renal Denervation in HFpEF.Journal of clinical medicine · 2025Review
- Health-related quality of life across heart failure categories: associations with clinical characteristics and outcomes.ESC heart failure · 2025Article
- Cardioneuroablation in the Management of Vagally Mediated Bradyarrhythmias-A Comprehensive Review of Ongoing Randomized Controlled Trials.Journal of clinical medicine · 2025Review
- Heart Failure with Preserved Ejection Fraction in Egypt: An Expert Opinion.Global heart · 2025Review
- Global epidemiology of heart failure.Nature reviews. Cardiology · 2024Review
- Assessing the diversity and determinants of health-related quality of life measures in patients with acute heart failure.ESC heart failure · 2024Article
- Is atrial fibrillation in HFpEF a distinct phenotype? Insights from multiparametric MRI and circulating biomarkers.BMC cardiovascular disorders · 2024Article
- High intensity interval training vs. moderate intensity continuous training on aerobic capacity and functional capacity in patients with heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Review
- Knowledge about self-efficacy and outcomes in patients with heart failure and reduced ejection fraction.European journal of heart failure · 2023Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThis study sought to compare the performance of 2 health-related quality of life (HRQOL) questionnaires in patients with heart failure with preserved ejection fraction (HFpEF).
backgroundThe ability to accurately assess HRQOL over time is important in the care of patients with heart failure. The validity and reliability of HRQOL tools including the Minnesota Living with Heart Failure Questionnaire (MLHFQ) and the Kansas City Cardiomyopathy Questionnaire (KCCQ) has not been fully determined or compared in patients with HFpEF.
methodsAmong patients with stable chronic HFpEF enrolled in the NEAT (Nitrate Effect on Activity Tolerance in Heart Failure) trial (n = 110), the study evaluated and compared reliability, validity, and responsiveness to change of the MLHFQ and KCCQ at baseline, 6 weeks, and 12 weeks.
resultsInternal consistency was good and comparable for MLHFQ and KCCQ domains measuring similar aspects of HRQOL at baseline including the MLHFQ physical (Cronbach's α = 0.93) compared with the KCCQ clinical summary (α = 0.91), and the MLHFQ emotional (α = 0.92) compared with the KCCQ quality of life (α = 0.87). Correlations with New York Heart Association functional class (Spearman rho; r
conclusionsThese data suggest that both the MLHFQ and KCCQ are reliable and valid tools to assess HRQOL in HFpEF. The KCCQ was more strongly correlated with baseline functional status parameters, while the MLHFQ was more responsive to improvement in 6MWT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.