Evidence map›Paper›PMID 29885760›Full record

ArticleJournal of dermatological science2018

TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.

Senthilnath Lakshmanachetty, Velmurugan Balaiya, Linda K Johnson, Maranke I Koster

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dermatological science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Senthilnath LakshmanachettyDepartment of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States; Gates Center for Regenerative Medicine, Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States.
Velmurugan BalaiyaDepartment of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States; Gates Center for Regenerative Medicine, Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States.
Linda K JohnsonDepartment of Pathology, Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States.
Maranke I KosterDepartment of Ophthalmology, Department of Pathology, Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, United States. Electronic address: maranke.koster@ucdenver.edu.
University of Colorado Denver · USGates (United States) · US

Funding

The role of p63 in hair follicle stem cells and cancerR01AR061506 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI KOSTER, MARANKE I. · 2011 to 2015
$1.7M
NIAMS NIH HHS R01 AR061506
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Wnt Signaling Pathway9,10-Dimethyl-1,2-benzanthraceneAnimalsCarcinoma, Squamous CellCell DifferentiationCell LineCell ProliferationCell Transformation, NeoplasticGene Expression Regulation, NeoplasticGenetic Predisposition to DiseaseHumansMice, KnockoutMice, NudePhosphoproteinsSkin NeoplasmsTetradecanoylphorbol Acetate9,10-Dimethyl-1,2-benzanthracenePhosphoproteinsTetradecanoylphorbol AcetateTP63 protein, humanTrans-ActivatorsTranscription FactorsTrp63 protein, mouseTumor Suppressor Proteins

Identifiers

PMID29885760
PMCPMC6151152
OpenAlexW2805314571

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.