ArticleAnnals of clinical microbiology and antimicrobials2018
Infectious disease burden and antibiotic prescribing in primary care in Israel.
Article in Annals of clinical microbiology and antimicrobials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
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- Tools and challenges in the use of routine clinical data for antimicrobial resistance surveillance.npj antimicrobials and resistance · 2025Review
- Silver Nanoparticles Functionalized with Polymeric Substances to Reduce the Growth of Planktonic and Biofilm Opportunistic Pathogens.International journal of molecular sciences · 2025Article
- Qualitative enquiry on factors affecting antibiotic prescribing at primary healthcare facilities in Addis Ababa, Ethiopia.Frontiers in medicine · 2024Article
- Management of urinary tract infections in the community: a clinical audit and patient survey.BJGP open · 2023Article
- Comments by Microbiologists for Interpreting Antimicrobial Susceptibility Testing and Improving the Appropriateness of Antibiotic Therapy in Community-Acquired Urinary Tract Infections: A Randomized Double-Blind Digital Case-Vignette Controlled Superiority Trial.Antibiotics (Basel, Switzerland) · 2023Article
- Antibiotics for gastroenteritis in general practice and out-of-hour services in Norway 2006-15.Family practice · 2022Article
- Spectrum of antibiotic resistance in UTI caused by Escherichia coli among HIV-infected patients in Uganda: a cross-sectional study.BMC infectious diseases · 2021Article
- Inter-prescriber variability in the decision to prescribe antibiotics to febrile patients attending primary care in Myanmar.JAC-antimicrobial resistance · 2021Article
- Systematic Review on the Impact of Guidelines Adherence on Antibiotic Prescription in Respiratory Infections.Antibiotics (Basel, Switzerland) · 2020Review
- Personal clinical history predicts antibiotic resistance of urinary tract infections.Nature medicine · 2019Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotics are frequently prescribed at many of the visits to primary care clinics, often for conditions for which they provide no benefit, including viral respiratory tract infections.
objectivesThe aim was to evaluate primary care visits due to infectious diseases, and to estimate antibiotic prescribing and antibiotic dispensing by pharmacies.
methodsDiagnosis of infectious disease, antibiotic prescribing and dispensing data at the individual patient level were extracted for 2015 from Clalit Health Services' electronic medical records and linked to determine the condition for which the antimicrobial was prescribed.
resultsThere were 6.6 million visits due to infections, representing 22% of all primary care visits. The most common events were upper respiratory tract infections (38%) and pharyngitis (10%). Highest prescription rates were for urinary tract infections (80%), otitis media (64%), pharyngitis (71%), sinusitis (63%), and lower respiratory tract infections (76%). The highest rates of undispensed prescriptions were for acute gastroenteritis, urinary tract infections, and pharyngitis (24, 23, and 16%, respectively).
conclusionsInfectious diseases constitute a heavy burden on primary care, with overprescribing of antibiotics. Intervention to reduce unwarranted antibiotic use is needed. In pediatric care, interventions should focus on better controlling antibiotic consumption and encouraging adherence to guidelines for upper respiratory tract infections, pharyngitis, and otitis media. In adults interventions should aim to monitor antibiotic prescribing for upper respiratory tract infections and improve adherence to guidelines for urinary tract infections.
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