Evidence map›Paper›PMID 29885327›Full record

ReviewJournal of molecular biology2018

From Atoms to Cells: Using Mesoscale Landscapes to Construct Visual Narratives.

David S Goodsell, Margaret A Franzen, Tim Herman

Abstract readReview
In one paragraph

Review in Journal of molecular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. A Concise Review of Biomolecule Visualization.Current issues in molecular biology · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Integrative illustration of a JCVI-syn3A minimal cell.Journal of integrative bioinformatics · 2022
    Article
  8. Building Structural Models of a Whole Mycoplasma Cell.Journal of molecular biology · 2022
    Article
  9. Article
  10. Bayesian metamodeling of complex biological systems across varying representations.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Challenges in protein docking.Current opinion in structural biology · 2020
    Review
  16. Art and Science of the Cellular Mesoscale.Trends in biochemical sciences · 2020
    Review
  17. Review
  18. Integrative Modeling and Visualization of Exosomes.The Journal of biocommunication · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David S GoodsellDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; RCSB Protein Data Bank & Center for Integrative Proteomics Research, Rutgers State University, Piscataway, NJ 08854, USA. Electronic address: goodsell@scripps.edu.
Margaret A FranzenCenter for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, WI 53202, USA.
Tim HermanCenter for BioMolecular Modeling, Milwaukee School of Engineering, Milwaukee, WI 53202, USA.

Funding

Modeling and Interacting with the Visible Molecular CellR01GM120604 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI AUTIN, LUDOVIC · 2016 to 2025
$4.2M
The Science of COVID-19 VaccinesR25GM129218 · NIGMS · MILWAUKEE SCHOOL OF ENGINEERING · PI HERMAN, TIM M. · 2018 to 2021
$1.1M
Science and Ethics of Genome EngineeringR25OD023723 · OD · MILWAUKEE SCHOOL OF ENGINEERING · PI HERMAN, TIM M. · 2017 to 2017
$270k
NIGMS NIH HHS R01 GM120604NIGMS NIH HHS R25 GM129218NIH HHS R25 OD023723
6 · The paper itself

Abstract

Modeling and visualization of the cellular mesoscale, bridging the nanometer scale of molecules to the micrometer scale of cells, is being studied by an integrative approach. Data from structural biology, proteomics, and microscopy are combined to simulate the molecular structure of living cells. These cellular landscapes are used as research tools for hypothesis generation and testing, and to present visual narratives of the cellular context of molecular biology for dissemination, education, and outreach.

Indexed as

Models, BiologicalModels, MolecularAnimalsCell BiologyCytological TechniquesHumansMolecular Biologycellular mesoscaleintegrative structural biologymesoscale modelingmolecular graphicsscience education

Identifiers

PMID29885327
PMCPMC6186495

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.