ArticleScientific reports2018
Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 54 citations in OpenAlex.
- Magneto-Photonic Gene Circuit for Minimally Invasive Control of Gene Expression in Mammalian Cells.ACS omega · 2026Article
- The Coli Toolkit (CTK): An Extension of the Modular Yeast Toolkit for Use inACS synthetic biology · 2026Article
- T Cell Receptor Co-Stimulation Through Magnetogenetic Tools: A Platform for Wireless Rewiring of Cellular Signaling.ACS omega · 2026Article
- Magneto-Photonic Gene Circuit for Minimally Invasive Control of Gene Expression in Mammalian Cells.bioRxiv : the preprint server for biology · 2025Article
- Using Manganese-Enhanced MRI to visualize Magnetogenetic-based Neuromodulation.bioRxiv : the preprint server for biology · 2025Article
- Open-source magnetic system for wireless neuromodulations in vitro and for untethered brain stimulation in vivo.Scientific reports · 2025Article
- A conserved phenylalanine motif among teleost fish provides insight for improving electromagnetic perception.Open biology · 2024Article
- Magnetogenetics as a promising tool for controlling cellular signaling pathways.Journal of nanobiotechnology · 2024Review
- A conserved phenylalanine motif among Teleost fish provides insight for improving electromagnetic perception.bioRxiv : the preprint server for biology · 2024Article
- Review
- Theranostics - a sure cure for cancer after 100 years?Theranostics · 2024Review
- Magnetogenetic stimulation inside MRI induces spontaneous and evoked changes in neural circuits activity in rats.Frontiers in neuroscience · 2024Article
- Single-domain magnetic particles with motion behavior under electromagnetic AC and DC fields are a fatal cargo in Metropolitan Mexico City pediatric and young adult early Alzheimer, Parkinson, frontotemporal lobar degeneration and amyotrophic lateral sclerosis and in ALS patients.Frontiers in human neuroscience · 2024Article
- A putative design for the electromagnetic activation of split proteins for molecular and cellular manipulation.Frontiers in bioengineering and biotechnology · 2024Article
- Magnetogenetic stimulation inside MRI induces spontaneous and evoked changes in neural circuits activity in rats.bioRxiv : the preprint server for biology · 2023Article
- Regulation of myogenesis and adipogenesis by the electromagnetic perceptive gene.Scientific reports · 2023Article
- Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells.Open biology · 2023Article
- Frequency-dependent avoidance movement of glass catfish in response to sinusoidal electrical stimulation and associated spiking patterns of electroreceptors.Biology open · 2023Article
- Peripheral Nerve Injury Induces Changes in the Activity of Inhibitory Interneurons as Visualized in Transgenic GAD1-GCaMP6s Rats.Biosensors · 2022Article
- Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research.Journal of visualized experiments : JoVE · 2021Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
Abstract
The Kryptopterus bicirrhis (glass catfish) is known to respond to electromagnetic fields (EMF). Here we tested its avoidance behavior in response to static and alternating magnetic fields stimulation. Using expression cloning we identified an electromagnetic perceptive gene (EPG) from the K. bicirrhis encoding a protein that responds to EMF. This EPG gene was cloned and expressed in mammalian cells, neuronal cultures and in rat's brain. Immunohistochemistry showed that the expression of EPG is confined to the mammalian cell membrane. Calcium imaging in mammalian cells and cultured neurons expressing EPG demonstrated that remote activation by EMF significantly increases intracellular calcium concentrations, indicative of cellular excitability. Moreover, wireless magnetic activation of EPG in rat motor cortex induced motor evoked responses of the contralateral forelimb in vivo. Here we report on the development of a new technology for remote, non-invasive modulation of cell function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.