Evidence map›Paper›PMID 29884772›Full record

ArticleThe Journal of biological chemistry2018

Peroxisomal monoubiquitinated PEX5 interacts with the AAA ATPases PEX1 and PEX6 and is unfolded during its dislocation into the cytosol.

Ana G Pedrosa, Tânia Francisco, Diana Bicho, Ana F Dias, Aurora Barros-Barbosa, Vera Hagmann, Gabriele Dodt, Tony A Rodrigues, Jorge E Azevedo

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Building peroxisomes: perspectives on plant peroxins.Biochemical Society transactions · 2026
    Review
  2. Article
  3. Polyunsaturated fatty acid metabolism in the retinal pigment epithelium and its association with outer retinal disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  4. Article
  5. Article
  6. PEX1The Journal of biological chemistry · 2025
    Article
  7. Review
  8. Potential biomarkers in hypoglycemic brain injury.Forensic science, medicine, and pathology · 2024
    Article
  9. Review
  10. Mammalian pexophagy at a glance.Journal of cell science · 2024
    Review
  11. Article
  12. The peroxisome: an update on mysteries 3.0.Histochemistry and cell biology · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana G PedrosaInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Tânia FranciscoInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Diana BichoInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Ana F DiasInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Aurora Barros-BarbosaInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Vera HagmannInterfakultäres Institut für Biochemie, Universität Tübingen, Hoppe Seyler Strasse 4, 72076 Tübingen, Germany.
Gabriele DodtInterfakultäres Institut für Biochemie, Universität Tübingen, Hoppe Seyler Strasse 4, 72076 Tübingen, Germany.
Tony A RodriguesInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Jorge E AzevedoInstituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Biologia Molecular e Celular (IBMC), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal. Electronic address: jazevedo@ibmc.up.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PEX1 and PEX6 are two members of the

Indexed as

Protein Interaction MapsATPases Associated with Diverse Cellular ActivitiesCytosolHumansMembrane ProteinsModels, MolecularPeroxisomesPeroxisome-Targeting Signal 1 ReceptorProtein TransportProtein UnfoldingUbiquitinUbiquitinationATPases Associated with Diverse Cellular ActivitiesMembrane ProteinsPeroxisome-Targeting Signal 1 ReceptorPEX1 protein, humanPEX5 protein, humanPEX6 protein, humanUbiquitinATPases associated with diverse cellular activities (AAA)peroxisomePEX1PEX5PEX6protein sortingprotein translocationubiquitin

Identifiers

PMID29884772
PMCPMC6065197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.