Evidence map›Paper›PMID 29884750›Full record

ArticleThe Journal of cell biology2018

Extracellular vesicles direct migration by synthesizing and releasing chemotactic signals.

Paul W Kriebel, Ritankar Majumdar, Lisa M Jenkins, Hiroshi Senoo, Weiye Wang, Sonia Ammu, Song Chen, Kedar Narayan, Miho Iijima, Carole A Parent

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 80 citations in OpenAlex.

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  14. Review
  15. Hydrogel Design to Understand and Guide 3D Cell Migration.Regenerative engineering and translational medicine · 2025
    Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Paul W KriebelLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Ritankar MajumdarLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD ritankar@umich.edu.ORCID 0000-0001-6624-0187
Lisa M JenkinsLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.ORCID 0000-0003-1245-1338
Hiroshi SenooDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD.
Weiye WangLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Sonia AmmuLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-2891-175X
Song ChenLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Kedar NarayanCenter for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.ORCID 0000-0001-7982-6494
Miho IijimaDepartment of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD.
Carole A ParentLaboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD parentc@umich.edu.ORCID 0000-0002-1518-1452
National Institutes of Health · USJohns Hopkins University · US

Funding

CPTR - Mass Spectrometry UnitZICBC011430 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JENKINS, LISA · 2012 to 2025
$9.4M
Lipid Signaling in ChemotaxisR01GM084015 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI IIJIMA, MIHO · 2009 to 2019
$2.9M
CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001ENIGMS NIH HHS R01 GM084015
6 · The paper itself

Abstract

Chemotactic signals are relayed to neighboring cells through the secretion of additional chemoattractants. We previously showed in

Indexed as

ChemotaxisATP-Binding Cassette TransportersCell MovementCyclic AMPDictyosteliumExtracellular VesiclesMass SpectrometryProteomeSignal TransductionATP-Binding Cassette TransportersCyclic AMPProteome

Identifiers

PMID29884750
PMCPMC6080930
OpenAlexW2805170780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.