Evidence map›Paper›PMID 29884665›Full record

ArticleBMJ case reports2018

Dangerous mistake: an accidental caffeine overdose.

Ana Andrade, Catarina Sousa, Mónica Pedro, Martinho Fernandes

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

  1. Toxidromes.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2022
    Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ana AndradeDepartment of Internal Medicine, Centro Hospitalar Barreiro Montijo EPE, Barreiro, Portugal.
Catarina SousaDepartment of Cardiology, Centro Hospitalar Barreiro Montijo EPE, Barreiro, Portugal.
Mónica PedroDepartment of Internal Medicine, Centro Hospitalar Barreiro Montijo EPE, Barreiro, Portugal.
Martinho FernandesDepartment of Internal Medicine, Centro Hospitalar Barreiro Montijo EPE, Barreiro, Portugal.
Centro De Medicina Veterinária Anjos De Assis · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caffeine (1,3,7-trimethylxanthine) is a natural product commonly presented in food's composition, beverages and medicinal products. Generally, it is thought to be safe under normal dosage, yet it can be fatal in case of severe intoxication. We report a case of a healthy 32-year-old woman who went to the local emergency department (ED) 30 min after ingesting, accidentally, 5000 mg of anhydrous caffeine for a preworkout supplement. At the ED, she presented an episode of presyncope followed by agitation. ECG showed polymorphic broad complex QRS tachycardia and arterial blood gas revealed metabolic acidaemia with severe hypokalemia. The dysrhythmia was successfully treated with intravenous propranolol. Acid-base and hydroelectrolytic disorders were also corrected. A persistent sinus tachycardia was observed in the first 2 days in the ward and 5 days later she was discharged asymptomatic with internal medicine follow-up.

Indexed as

AcidosisAdministration, IntravenousAdultAftercareAnti-Arrhythmia AgentsCaffeineDietary SupplementsElectrocardiographyFemaleHumansHypokalemiaPropranololPsychomotor AgitationRare DiseasesSyncopeTachycardiaAnti-Arrhythmia AgentsCaffeinePropranololarrhythmiaspoisoningvitamins and supplements

Identifiers

PMID29884665
PMCPMC6011436
OpenAlexW2805837542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.