Evidence map›Paper›PMID 29884664›Full record

ArticleBMJ case reports2018

Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis.

Erica Sieg, Michael Brook, Jenny Linnoila, Stephen VanHaerents

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erica SiegPsychiatry and Behavioral Sciences, Northwestern Memorial Hospital, Chicago, Illinois, USA.
Michael BrookPsychiatry and Behavioral Sciences, Northwestern Memorial Hospital, Chicago, Illinois, USA.
Jenny LinnoilaDepartment of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Stephen VanHaerentsDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID http://orcid.org/0000-0003-0759-4414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 1-year follow-up of a young woman with anti-N-methyl-D-aspartate receptor encephalitis. Management of autoimmune encephalitis remains challenging as objective and clinically relevant biomarkers are sought, which allow for the monitoring of treatment response. While further investigation is required, we believe that this case highlights the importance of following a comprehensive neuropsychological profile as a clinically relevant biomarker to guide therapeutic decision-making. By relying on the neuropsychological assessment of the patient, treatment with more toxic medications was avoided and her antiepileptic drug regimen was simplified.

Indexed as

AdultAnticonvulsantsAntineoplastic Agents, ImmunologicalAnti-N-Methyl-D-Aspartate Receptor EncephalitisAutoimmune Diseases of the Nervous SystemConfusionElectroencephalographyEpilepsia Partialis ContinuaFemaleHumansImmunosuppressive AgentsMagnetic Resonance ImagingMonitoring, PhysiologicNeuropsychological TestsPlasma ExchangeRare DiseasesAnticonvulsantsAntineoplastic Agents, ImmunologicalImmunosuppressive AgentsReceptors, N-Methyl-D-AspartateRituximabSteroidsclinical neurophysiologyepilepsy and seizuresimmunologymemory disorders (psychiatry)

Identifiers

PMID29884664
PMCPMC6011453

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.