Trial reportCirculation. Cardiovascular quality and outcomes2018
Cluster-Randomized Trial to Evaluate a Centralized Clinical Pharmacy Service in Private Family Medicine Offices.
Trial report in Circulation. Cardiovascular quality and outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01983813 (Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care), which is not on this map. Cited by 21 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improved Cardiovascular Risk Reduction to Enhance Rural Primary Care
Who cites it
21 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Telehealth-guided provider-to-provider communication to improve rural health: A systematic review.Journal of telemedicine and telecare · 2024Pooled it
- Involving community pharmacists in interprofessional collaboration in primary care: a systematic review.BMC primary care · 2024Pooled it
- Interprofessional collaboration in primary care: what effect on patient health? A systematic literature review.BMC primary care · 2023Pooled it
- Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes.The Cochrane database of systematic reviews · 2023Pooled it
- American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022Guideline
- Digital Health Interventions by Clinical Pharmacists: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- A pharmacist intervention for monitoring and treating hypertension using bidirectional texting: PharmText BP.Contemporary clinical trials · 2020Trial
- The Spectrum of Clinical Pharmacy Services in a Non-University Hospital-A Comprehensive Characterization Including a Risk Assessment for Drug-Related Problems and Adverse Drug Reactions.Pharmacy (Basel, Switzerland) · 2025Article
- Effectiveness of Pharmacist-Led Intervention on Medication Adherence in Chronic Diseases: A Systematic Review of Randomized Controlled Trials.Patient preference and adherence · 2025Review
- Do clinical decision support tools improve quality of care outcomes in the primary prevention of cardiovascular disease: A systematic review and meta-analysis.American journal of preventive cardiology · 2024Article
- Two randomized controlled trials of nudges to encourage referrals to centralized pharmacy services for evidence-based statin initiation in high-risk patients: Rationale and design of the SUPER LIPID program.American heart journal · 2024Article
- Pharmacist-Led Follow-Up Program for Rural Patients with Acute Coronary Syndrome: The PLURAL-ACS Pilot Program.The Canadian journal of hospital pharmacy · 2024Article
- Trends in guideline implementation: an updated scoping review.Implementation science : IS · 2022Article
- Research and Scholarly Methods: Pragmatic Clinical Trials.Journal of the American College of Clinical Pharmacy : JACCP · 2022Article
- A cluster randomized trial to evaluate a centralized remote clinical pharmacy service in large, health system primary care clinics.Journal of the American College of Clinical Pharmacy : JACCP · 2021Article
- Dissemination of a telehealth cardiovascular risk service: The CVRS live protocol.Contemporary clinical trials · 2021Article
- Opportunity for Pharmacists in Telehealth, Team-Based Care: Clinical Inertia.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2020Article
- The Emerging Role of Community Pharmacists in Remote Patient Monitoring Services.Pharmacy (Basel, Switzerland) · 2020Article
- Evaluation of a clinical pharmacist team-based telehealth intervention in a rural clinic setting: a pilot study of feasibility, organizational perceptions, and return on investment.Pilot and feasibility studies · 2020Article
- Partnering With Pharmacists to Reduce Cardiovascular Risk in Outpatient Settings.Journal of the American Heart Association · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe use of clinical pharmacists in primary care has improved the control of several chronic cardiovascular conditions. However, many private physician practices lack the resources to implement team-based care with pharmacists. The purpose of this study was to evaluate whether a centralized, remote, clinical pharmacy service could improve guideline adherence and secondary measures of cardiovascular risk in primary care offices in rural and small communities. METHODS AND
resultsThis study was a prospective trial in 12 family medicine offices cluster randomized to either the intervention or usual care. The intervention was delivered for 12 months, and subjects had research visits at baseline and 12 months. The primary outcome was adherence to guidelines, and secondary outcomes included changes in key cardiovascular risk factors and preventative health measures. We enrolled 302 subjects. There was no improvement in the Guideline Advantage score from baseline to 12 months in the control group (64.7% versus 63.1%, respectively;
conclusionsThe centralized, remote pharmacist intervention was successfully implemented. The improvements in outcomes were modest, in part because of higher than expected baseline guideline adherence. Future studies of this model should focus on patients with uncontrolled conditions at high risk for cardiovascular events. CLINICAL
trial registrationURL: https://www.clinicaltrials.gov. Unique identifier: NCT 01983813.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.