Evidence map›Paper›PMID 29884614›Full record

ArticleG3 (Bethesda, Md.)2018

A Variable Polyglutamine Repeat Affects Subcellular Localization and Regulatory Activity of a

Anthony C Bryan, Jin Zhang, Jianjun Guo, Priya Ranjan, Vasanth Singan, Kerrie Barry, Jeremy Schmutz, Deborah Weighill, Daniel Jacobson, Sara Jawdy and 3 more

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Possible Role for Allelic Variation in YeastFrontiers in microbiology · 2021
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Anthony C BryanBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Jin ZhangBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.ORCID 0000-0002-8397-5078
Jianjun GuoBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Priya RanjanBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Vasanth SinganU.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598.
Kerrie BarryU.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598.
Jeremy SchmutzU.S. Department of Energy Joint Genome Institute, Walnut Creek, CA 94598.
Deborah WeighillBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Daniel JacobsonBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Sara JawdyBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.
Gerald A TuskanBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831.ORCID 0000-0003-0106-1289
Jin-Gui ChenBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 chenj@ornl.gov mucherow@ornl.gov.ORCID 0000-0002-1752-4201
Wellington MucheroBiosciences Division and BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 chenj@ornl.gov mucherow@ornl.gov.ORCID 0000-0002-0200-9856
Oak Ridge National Laboratory · USJoint Genome Institute · USHudsonAlpha Institute for Biotechnology · USUniversity of Tennessee at Knoxville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyglutamine (polyQ) stretches have been reported to occur in proteins across many organisms including animals, fungi and plants. Expansion of these repeats has attracted much attention due their associations with numerous human diseases including Huntington's and other neurological maladies. This suggests that the relative length of polyQ stretches is an important modulator of their function. Here, we report the identification of a

Indexed as

Active Transport, Cell NucleusAllelesCell NucleusDNA-Binding ProteinsPeptidesPlant ProteinsPopulusProtein Sorting SignalsDNA-Binding ProteinsPeptidesPlant ProteinspolyglutamineProtein Sorting Signalscell wallligninPolyQPopulussubcellular localization

Identifiers

PMID29884614
PMCPMC6071607
OpenAlexW2806933088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.