ReviewThe Journal of allergy and clinical immunology2018
Chronic obstructive pulmonary disease subpopulations and phenotyping.
Review in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Clinical Observation of General Anesthesia Combined with Spinal Anesthesia in Elderly Patients with Chronic Obstructive Pulmonary Disease.BioMed research international · 2022Trial
- Molecular and Cellular Mechanisms Responsible for Beneficial Effects of Mesenchymal Stem Cell-Derived Product "Exo-d-MAPPS" in Attenuation of Chronic Airway Inflammation.Analytical cellular pathology (Amsterdam) · 2020Trial
- Fibrocytes with different phenotypes are recruited in chronic obstructive pulmonary disease.Scientific reports · 2026Article
- MPO-Mediated oxidative stress regulates lung tissue damage in T-COPD through activation of the NLRP3 inflammasome.Histology and histopathology · 2026Article
- Dysbiosis of the nasal microbiome is associated with prospective acute exacerbation of COPD.Microbiome · 2026Article
- Association of automated quantified emphysema and interstitial lung abnormality with survival in non-small cell lung cancer.Insights into imaging · 2026Article
- Predictive validity of chronic obstructive pulmonary disease phenotypes in inpatient elective surgery: a population-based study.British journal of anaesthesia · 2025Article
- Article
- An integrated machine learning model of transcriptomic genes in multi-center chronic obstructive pulmonary disease reveals the causal role of TIMP4 in airway epithelial cell.Respiratory research · 2025Article
- Lower bioelectrical impedance phase angle is associated with COPD and is a marker for increased risks in elderly COPD patients.Frontiers in medicine · 2025Article
- Differentiating Emphysema From Emphysema-Dominated COPD Patients with CT Imaging Feature and Machine Learning.International journal of chronic obstructive pulmonary disease · 2025Article
- Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach.International journal of chronic obstructive pulmonary disease · 2025Article
- Identifying KL-6-Associated Immune Cell Signatures and Key Genes in Emphysematous COPD.Journal of inflammation research · 2025Article
- Eosinophil count and clinical outcome in patients with acute exacerbation of Chronic obstructive pulmonary disease.Journal of preventive medicine and hygiene · 2024Article
- Effects of the teach-back method on the health status of patients with chronic obstructive pulmonary disease: a real-world community-based cluster-randomized controlled trial.Journal of thoracic disease · 2024Article
- Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression.International journal of molecular sciences · 2024Review
- Relationship between Respiratory Microbiome and Systemic Inflammatory Markers in COPD: A Pilot Study.International journal of molecular sciences · 2024Article
- Single-Breath Simultaneous Measurement of DLInternational journal of chronic obstructive pulmonary disease · 2024Observational
- Prospective study of protein intake and mortality among US adults with chronic obstructive pulmonary disease.Frontiers in nutrition · 2024Article
- Significant role of circRNA BBS9 in chronic obstructive pulmonary disease via miRNA-103a-3p/BCL2L13.BMC pulmonary medicine · 2023Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The diagnosis and treatment of chronic obstructive pulmonary disease (COPD) has been based largely on a one-size-fits-all approach. Diagnosis of COPD is based on meeting the physiologic criteria of fixed obstruction in forced expiratory flows and treatment focus on symptomatic relief, with limited effect on overall prognosis. However, patients with COPD have distinct features that determine very different evolutions of the disease. In this review we highlight distinct subgroups of COPD characterized by unique pathophysiologic derangements, response to treatment, and disease progression. It is likely that identification of subgroups of COPD will lead to discovery of much needed disease-modifying therapeutic approaches. We argue that a precision approach that integrates multiple dimensions (clinical, physiologic, imaging, and endotyping) is needed to move the field forward in the treatment of this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.