ArticleBMC evolutionary biology2018
Embryonic expression patterns and phylogenetic analysis of panarthropod sox genes: insight into nervous system development, segmentation and gonadogenesis.
Article in BMC evolutionary biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 86 citations in OpenAlex.
- Conserved and diverged embryonic expression patterns of panarthropod NK-Cluster genes and new evidence for CRE-shuffling.BMC ecology and evolution · 2026Article
- Early nervous system development in the chaetognathFrontiers in cell and developmental biology · 2026Article
- Real-time imaging on a microwell device allows first insights into the embryonic development of the ubiquitous and notorious scabies parasite.Scientific reports · 2025Article
- The cryptonephridial/rectal complex: an evolutionary adaptation for water and ion conservation.Biological reviews of the Cambridge Philosophical Society · 2025Review
- Single-cell sequencing suggests a conserved function of Hedgehog-signalling in spider eye development.EvoDevo · 2024Article
- Single-cell RNA sequencing of mid-to-late stage spider embryos: new insights into spider development.BMC genomics · 2024Article
- New insights into mesoderm and endoderm development, and the nature of the onychophoran blastopore.Frontiers in zoology · 2024Article
- Expression of posterior Hox genes and opisthosomal appendage development in a mygalomorph spider.Development genes and evolution · 2023Article
- Evolution of the Spider Homeobox Gene Repertoire by Tandem and Whole Genome Duplication.Molecular biology and evolution · 2023Article
- Genome-Wide Identification, Evolutionary and Mutational Analysis of the Buffalo Sox Gene Family.Animals : an open access journal from MDPI · 2023Article
- An In Vivo Whole-Transcriptomic Approach to Assess Developmental and Reproductive Impairments Caused by Flumequine inInternational journal of molecular sciences · 2023Article
- Review of extra-embryonic tissues in the closest arthropod relatives, onychophorans and tardigrades.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- The Nasonia pair-rule gene regulatory network retains its function over 300 million years of evolution.Development (Cambridge, England) · 2022Article
- Lack of evidence for conserved parasegmental grooves in arthropods.Development genes and evolution · 2022Article
- Article
- A chelicerate Wnt gene expression atlas: novel insights into the complexity of arthropod Wnt-patterning.EvoDevo · 2021Article
- The Evolution of Sox Gene Repertoires and Regulation of Segmentation in Arachnids.Molecular biology and evolution · 2021Article
- Time and space in segmentation.Interface focus · 2021Article
- Panarthropod tiptop/teashirt and spalt orthologs and their potential role as "trunk"-selector genes.EvoDevo · 2021Article
- Article
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Authors and funding
11 authors at 1 institution in 1 country.
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Abstract
backgroundSox (Sry-related high-mobility-group box) genes represent important factors in animal development. Relatively little, however, is known about the embryonic expression patterns and thus possible function(s) of Sox genes during ontogenesis in panarthropods (Arthropoda+Tardigrada+Onychophora). To date, studies have been restricted exclusively to higher insects, including the model system Drosophila melanogaster, with no comprehensive data available for any other arthropod group, or any tardigrade or onychophoran.
resultsThis study provides a phylogenetic analysis of panarthropod Sox genes and presents the first comprehensive analysis of embryonic expression patterns in the flour beetle Tribolium castaneum (Hexapoda), the pill millipede Glomeris marginata (Myriapoda), and the velvet worm, Euperipatoides kanangrensis (Onychophora). 24 Sox genes were identified and investigated: 7 in Euperipatoides, 8 in Glomeris, and 9 in Tribolium. Each species possesses at least one ortholog of each of the five expected Sox gene families, B, C, D, E, and F, many of which are differentially expressed during ontogenesis.
conclusionSox gene expression (and potentially function) is highly conserved in arthropods and their closest relatives, the onychophorans. Sox B, C and D class genes appear to be crucial for nervous system development, while the Sox B genes Dichaete (D) and Sox21b likely play an additional conserved role in panarthropod segmentation. The Sox B gene Sox21a likely has a conserved function in foregut and Malpighian tubule development, at least in Hexapoda. The data further suggest that Sox D and E genes are involved in mesoderm differentiation, and that Sox E genes are involved in gonadal development. The new data expand our knowledge about the expression and implied function of Sox genes to Mandibulata (Myriapoda+Pancrustacea) and Panarthropoda (Arthropoda+Onychophora).
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