ArticleNeurotoxicology and teratology
Prevalence and associated birth outcomes of co-use of Cannabis and tobacco cigarettes during pregnancy.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The prevalence of mental health-related multimorbidity during pregnancy: a systematic review and meta-analysis.BMC public health · 2026Pooled it
- Fetal Cannabis Exposure and Neonatal Outcomes: A Systematic Review and Meta-Analysis.Maternal and child health journal · 2025Pooled it
- Cannabis Use in Pregnancy and Neonatal Outcomes: A Systematic Review and Meta-Analysis.Cannabis and cannabinoid research · 2024Pooled it
- Birth, cognitive and behavioral effects of intrauterine cannabis exposure in infants and children: A systematic review and meta-analysis.Addiction (Abingdon, England) · 2024Pooled it
- Systematic Review: Polysubstance Prevalence Estimates Reported during Pregnancy, US, 2009-2020.Maternal and child health journal · 2023Pooled it
- Disparities in Healthcare Providers' Substance Use Detection Practices for Pregnant Patients.Journal of racial and ethnic health disparities · 2026Article
- A systematic review investigating prenatal cannabis and tobacco co-exposure: Impacts on neonatal, behavioral, cognitive and physiological outcomes.Drug and alcohol dependence reports · 2025Review
- Effects of Inhaled Tobacco and Cannabis Co-Use on Respiratory Health and Tobacco Cessation: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Meta-analysis of maternal and neonatal outcomes of cannabis use in pregnancy current to March 2024.Maternal health, neonatology and perinatology · 2025Review
- Maternal Prenatal Cannabis Use and Major Structural Birth Defects.Birth defects research · 2025Article
- Prenatal Cannabis Use and Neonatal Outcomes: A Systematic Review and Meta-Analysis.JAMA pediatrics · 2025Article
- Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course.Molecular psychiatry · 2025Article
- Cannabis use patterns, motivations, and reasons for abstinence in pregnancy.Frontiers in psychiatry · 2025Article
- Use and co-use of tobacco and cannabis before, during, and after pregnancy: A longitudinal analysis of waves 1-5 of the Population Assessment of Tobacco and Health (PATH) study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024Article
- Risk of Adverse Neonatal Outcomes After Combined Prenatal Cannabis and Nicotine Exposure.JAMA network open · 2024Article
- Prenatal Exposure to Cannabis: Effects on Childhood Obesity and Cardiometabolic Health.Current obesity reports · 2024Review
- Polysubstance use during pregnancy: The importance of screening, patient education, and integrating a harm reduction perspective.Drug and alcohol dependence · 2023Article
- Emerging Roles of Endocannabinoids as Key Lipid Mediators for a Successful Pregnancy.International journal of molecular sciences · 2023Review
- A systematic review ofFrontiers in pediatrics · 2023Review
- Simultaneous quantification of urinary tobacco and marijuana metabolites using solid-supported liquid-liquid extraction coupled with liquid chromatography tandem mass spectrometry.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Use of Cannabis and use of tobacco overlap, and co-use of Cannabis and tobacco has increased over the past decade among adults. The current study aims to document the prevalence and correlates of co-use of Cannabis and tobacco cigarettes among adult pregnant women utilizing secondary data from a larger study that compared and validated screeners for illicit and prescription drug use during pregnancy. Pregnant women (N = 500; 71% African American; 65% never married, average age of 28 years) were recruited from two urban University obstetric clinics between January and December 2017. Participants self-reported demographic, Cannabis, and tobacco cigarette use characteristics, and provided urine and hair samples for drug testing. Within two weeks after due date, research staff reviewed participants' electronic medical records to collect birth outcome data. Results showed that 9.0% reported co-use of Cannabis and tobacco, 12.1% reported Cannabis only use, 7.8% reported tobacco cigarette only use, and 71.1% reported no Cannabis or tobacco cigarette use in the past month. The birth outcomes to emerge as significant correlates of co-use of Cannabis and tobacco cigarettes were small head circumference, and the occurrence of birth defects, with the co-use group having the highest odds of a small head circumference [aOR: 5.7 (1.1-28.9)] and birth defects [aOR: 3.1 (1.2-8.3)] compared with other use groups. The Cannabis only group had 12 times higher odds of a stillbirth or miscarriage (aOR = 12.1). Screening and interventions to address concurrent Cannabis and tobacco use during pregnancy are needed, particularly among subpopulations with higher co-use rates. It is imperative to further explore and highlight the possible health implications of maternal co-use given the high prevalence rates found in this study sample.
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