Trial reportPloS one2018
Effects of a depression-focused internet intervention in slot machine gamblers: A randomized controlled trial.
Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 7 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Efficacy of prescription-eligible digital health applications for depression and generalized anxiety disorder in Germany: a systematic review and meta-analysis.Scientific reports · 2026Pooled it
- [Efficacy of internet-based interventions for depression available in Germany-A systematic review and meta-analysis].Der Nervenarzt · 2024Pooled it
- Attrition in Conversational Agent-Delivered Mental Health Interventions: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Effects of cognitive behavioral techniques for gambling on recovery defined by gambling, psychological functioning, and quality of life: A systematic review and meta-analysis.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023Pooled it
- Internet-based interventions for behavioral addictions: A systematic review.Journal of behavioral addictions · 2022Pooled it
- Identification of Behavior Change Techniques From Successful Web-Based Interventions Targeting Alcohol Consumption, Binge Eating, and Gambling: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Effectiveness of a tailored, integrative Internet intervention (deprexis) for depression: Updated meta-analysis.PloS one · 2020Pooled it
- Betting on change: An analysis of cognitive motivational behavior therapy versus referral to gamblers anonymous for gambling disorder.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025Trial
- A Self-Guided Internet-Based Intervention for the Reduction of Gambling Symptoms: A Randomized Clinical Trial.JAMA network open · 2024Trial
- A randomized controlled trial on a self-guided Internet-based intervention for gambling problems.Scientific reports · 2021Trial
- Feasibility, Acceptance, and Safety of Metacognitive Training for Problem and Pathological Gamblers (Gambling-MCT): A Pilot Study.Journal of gambling studies · 2021Trial
- Web-Based Intervention and Email-Counseling for Problem Gamblers: Results of a Randomized Controlled Trial.Journal of gambling studies · 2020Trial
- Determinants of Dropout From a Virtual Agent-Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study.JMIR mental health · 2025Article
- Top-funded companies offering digital health interventions for the prevention and treatment of depression: a systematic market analysis.Archives of public health = Archives belges de sante publique · 2024Article
- A Self-Applied Psychological Treatment for Gambling-Related Problems via The Internet: A Pilot, Feasibility Study.Journal of gambling studies · 2024Article
- Insights into insurance coverage for digital therapeutics: A qualitative study of US payer perspectives.Journal of managed care & specialty pharmacy · 2024Article
- Digital Health Applications in the Area of Mental Health.Deutsches Arzteblatt international · 2023Review
- Effectiveness of an Internet-Based Self-Guided Program to Treat Depression in a Sample of Brazilian Users: Randomized Controlled Trial.JMIR formative research · 2023Article
- The Dimensional Structure of the Gambling Attitudes and Beliefs Survey: Challenging the Assumption of the Unidimensionality of Gambling-Specific Cognitive Distortions.Journal of gambling studies · 2023Article
- Internet-delivered therapist-assisted cognitive behavioral therapy for gambling disorder: a randomized controlled trial.Frontiers in psychiatry · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProblematic and pathological gambling have been linked to depression. Despite a high demand for treatment and negative financial consequences, only a small fraction of problematic and pathological gamblers seek professional help. The existing treatment gap could be narrowed by providing low-threshold, anonymous internet-based interventions. The aim of the present study was to examine the acceptance and efficacy of an online-intervention for depression ("Deprexis") in a sample of problematic and pathological slot-machine gamblers. We hypothesized that the intervention group would show a greater reduction in both depressive and gambling-related symptoms compared to a wait-list control group.
methodA total of 140 individuals with self-reported gambling and mood problems were randomly allocated either to the intervention group or to a wait-list control group. After 8 weeks, all participants were invited for re-assessment. The Patient Health Questionnaire - 9 (PHQ-9) served as the primary outcome assessment. Problematic gambling was measured with the Pathological Gambling Adaptation of Yale-Brown Obsessive Compulsive Scale (PG-YBOCS) and the South Oaks Gambling Screen (SOGS). The trial is registered with the German Registry for Clinical Studies (DRKS00013888).
resultsITT analyses showed that the intervention led to a significant reduction in depressive symptoms as well as gambling-related symptoms compared to the control group, with moderate to strong effect sizes. PP analyses failed to yield significant results due to high rates of non-completion and limited statistical power. Moderator analyses indicated that Deprexis was particularly beneficial in reducing problematic gambling for those scoring high on baseline gambling-related symptoms and for those who gamble due to loneliness. DISCUSSION: Results of the present study suggest that Deprexis might be a useful adjunct to traditional interventions for the treatment of problematic gambling. The potential of internet-based interventions that are more targeted at issues specific to gambling should be evaluated in future studies.
trial registrationGerman Registry for Clinical Studies DRKS00013888.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.