Evidence map›Paper›PMID 29883417›Full record

ArticleInternational journal of molecular sciences2018

Protective Effects of 2-Amino-5,6-dihydro-4

Yuanyuan Li, Shaofan Kong, Fujun Yang, Wenqing Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Exploring the Diverse Therapeutic Applications of 1, 3-Thiazine: A Comprehensive Review.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
  5. Green Synthesis of 2-Mercapto 5,6-Dihydro-4Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuanyuan LiInstitute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical Collage, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin 300192, China. yuanyuanli0929@163.com.
Shaofan KongInstitute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical Collage, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin 300192, China. ksf226@126.com.
Fujun YangInstitute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical Collage, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin 300192, China. yangfj32@126.com.
Wenqing XuInstitute of Radiation Medicine, Chinese Academy of Medical Science and Peking Union Medical Collage, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin 300192, China. xuwenqing@irm-cams.ac.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ionizing radiation (IR) acts as an external stimulating factor, when it acts on the body, it will activate NF- κ B and cause the up-regulation of inducible nitric oxide synthase (iNOS) and induce a large amount of nitric oxide (NO) production. NO and other reactive nitrogen and oxygen species (RNS and ROS) can cause damage to biological molecules and affect their physiological functions. Our study investigated the protective role of 2-amino-5,6-dihydro-4

Indexed as

AnimalsHematopoietic SystemIntestinal MucosaIntestinesLipid PeroxidationMiceNitric OxideOxidative StressRadiation InjuriesRadiation-Protective AgentsReactive Nitrogen SpeciesReactive Oxygen SpeciesThiazines2-amino-5,6-dihydro-4H-1,3-thiazineNitric OxideRadiation-Protective AgentsReactive Nitrogen SpeciesReactive Oxygen SpeciesThiazines2-acetylamino-5,6-dihydro-4H-1,3-thiazine hydrobromide (2-AADT)2-amino-5,6-dihydro-4H-1,3-thiazine hydrobromide (2-ADT)hematopoieticintestinal injuryradioprotection

Identifiers

PMID29883417
PMCPMC5983608
OpenAlexW2803479159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.