Evidence map›Paper›PMID 29883392›Full record

ArticleNutrients2018

Milk-Related Symptoms and Immunoglobulin E Reactivity in Swedish Children from Early Life to Adolescence.

Jennifer L P Protudjer, Ola Olén, Mirja Vetander, Inger Kull, Erik Melén, Marianne van Hage, Magnus Wickman, Anna Bergström

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jennifer L P ProtudjerCenter for Occupational and Environmental Medicine, Stockholm County Council, 113 65 Stockholm, Sweden. jennifer.protudjer@ki.se.
Ola OlénClinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, 171 76 Stockholm, Sweden. Ola.Olen@ki.se.ORCID 0000-0002-5478-7019
Mirja VetanderInstitute for Environmental Medicine, Karolinska Institutet, 171 11 Stockholm, Sweden. mirja.gotze-vetander@sll.se.
Inger KullInstitute for Environmental Medicine, Karolinska Institutet, 171 11 Stockholm, Sweden. inger.kull@ki.se.
Erik MelénInstitute for Environmental Medicine, Karolinska Institutet, 171 11 Stockholm, Sweden. erik.melen@ki.se.
Marianne van HageDepartment of Medicine Solna, Immunology and Allergy Unit, Karolinska Institutet, and Karolinska University Hospital, 171 76 Stockholm, Sweden. marianne.van.hage@ki.se.
Magnus WickmanInstitute for Environmental Medicine, Karolinska Institutet, 171 11 Stockholm, Sweden. magnus.c.wickman@gmail.com.
Anna BergströmCenter for Occupational and Environmental Medicine, Stockholm County Council, 113 65 Stockholm, Sweden. anna.bergstrom@ki.se.
Karolinska Institutet · SEStockholm County Council · SEKarolinska University Hospital · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cow’s milk often causes symptoms in infants. Whereas, some continue to experience symptoms through childhood, others become tolerant. Yet, the ages at which persistence and tolerance occur are less clear. Thus, we examined the age of onset and persistence of milk-related symptoms from early life to adolescence, and Immunoglobulin E (IgE) milk reactivity, focusing on gender differences in a large, population-based birth cohort. Overall, 20.0% (537/2985) of children, with a comparable gender distribution, had early life milk-related symptoms. At 16y, approximately 2% (62/2985) children had persistent symptoms and high milk IgE levels (e.g., median at 4 years: 1.5 kU

Indexed as

Immune ToleranceAdolescentAdolescent DevelopmentAge DistributionAge of OnsetBiomarkersChildChild DevelopmentChild, PreschoolFemaleGastrointestinal DiseasesHumansImmunoglobulin EInfantMaleMilk HypersensitivityBiomarkersImmunoglobulin Eadolescentallergyanaphylaxischildfood hypersensitivityImmunoglobulin Emilk

Identifiers

PMID29883392
PMCPMC5986530
OpenAlexW2803454897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.