Evidence map›Paper›PMID 29883379›Full record

ArticleToxins2018

Domain II of

Fabian Müller, Tyler Cunningham, Richard Beers, Tapan K Bera, Alan S Wayne, Ira Pastan

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Fabian MüllerLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. fabian.mueller@uk-erlangen.de.
Tyler CunninghamLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. cunningham.tyler@gmail.com.
Richard BeersLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. beersr@dc37a.nci.nih.gov.
Tapan K BeraLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. berat@mail.nih.gov.
Alan S WayneChildren's Center for Cancer and Blood Diseases, Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Hospital Los Angeles, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA. awayne@chla.usc.edu.
Ira PastanLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. pastani@mail.nih.gov.ORCID 0000-0002-9223-0270
National Institutes of Health · USUniversity of Southern California · US

Funding

Immunotoxin Therapy of Solid and Hematopoietic Tumors: Preclinical StudiesZIABC008753 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PASTAN, IRA · 2009 to 2024
$33.1M
6 · The paper itself

Abstract

Moxetumomab pasudotox is a fusion protein of a CD22-targeting antibody and

Indexed as

Protein DomainsAnimalsAntineoplastic AgentsBacterial ToxinsCell Line, TumorDisease Models, AnimalExotoxinsHumansImmunotoxinsMicePrecursor Cell Lymphoblastic Leukemia-LymphomaPseudomonasTreatment OutcomeXenograft Model Antitumor AssaysAntineoplastic AgentsBacterial ToxinsExotoxinsimmunotoxin HA22Immunotoxinsacute lymphoblastic leukemiaB cell non-Hodgkin lymphomaCD22immunotoxinmantle cell lymphomaMoxetumomab pasudotoxtargeted therapy

Identifiers

PMID29883379
PMCPMC5983266
OpenAlexW2803505838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.