Evidence map›Paper›PMID 29883366›Full record

ArticleAging2018

Inactivation of hepatic ATRX in

Megan E Rowland, Yan Jiang, Frank Beier, Nathalie G Bérubé

Open access · greenAbstract read
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. ATRX: From Chromatin Remodeling to Disease.Genesis (New York, N.Y. : 2000) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Megan E RowlandDepartments of Paediatrics and Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Yan JiangDepartments of Paediatrics and Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Frank BeierChildren's Health Research Institute, London, ON, Canada.
Nathalie G BérubéDepartments of Paediatrics and Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Western University · CAChildren’s Health Research Institute · CA

Funding

Canadian Institutes for Health Research MOP#142369
6 · The paper itself

Abstract

ATRX is an ATP-dependent chromatin remodeler required for the maintenance of genomic integrity. We previously reported that conditional

Indexed as

AgingAnimalsBlood GlucoseForkhead Transcription FactorsGene Expression RegulationInsulin-Like Growth Factor ILiverMiceMice, TransgenicNerve Tissue ProteinsSubcutaneous FatThyroxineX-linked Nuclear ProteinAtrx protein, mouseBlood GlucoseForkhead Transcription FactorsFoxg1 protein, mouseinsulin-like growth factor-1, mouseInsulin-Like Growth Factor INerve Tissue ProteinsThyroxineX-linked Nuclear ProteinATRXIGF-1premature agingthyroid hormonetranscription

Identifiers

PMID29883366
PMCPMC6046231
OpenAlexW2805579587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.