Evidence map›Paper›PMID 29882898›Full record

ReviewMarine drugs2018

Developments of Cyanobacteria for Nano-Marine Drugs: Relevance of Nanoformulations in Cancer Therapies.

Vivek K Bajpai, Shruti Shukla, Sung-Min Kang, Seung Kyu Hwang, Xinjie Song, Yun Suk Huh, Young-Kyu Han

Abstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. NovelPharmaceuticals (Basel, Switzerland) · 2022
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. The Bioactivities of Phycocyanobilin from Spirulina.Journal of immunology research · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vivek K BajpaiDepartment of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul 04620, Korea. vbiotech04@gmail.com.
Shruti ShuklaDepartment of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul 04620, Korea. shrutishukla1983@gmail.com.
Sung-Min KangWCSL of Integrated Human Airway-on-a-chip, Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Korea. sungmin.kang21@gmail.com.
Seung Kyu HwangWCSL of Integrated Human Airway-on-a-chip, Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Korea. h3418kr@gmail.com.
Xinjie SongDepartment of Food Science and Technology, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do 38541, Korea. jesse.song@hotmail.com.
Yun Suk HuhWCSL of Integrated Human Airway-on-a-chip, Department of Biological Engineering, Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Korea. yunsuk.huh@inha.ac.kr.
Young-Kyu HanDepartment of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro 1-gil, Seoul 04620, Korea. ykenergy@dongguk.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current trends in the application of nanomaterials are emerging in the nano-biotechnological sector for development of medicines. Cyanobacteria (blue-green algae) are photosynthetic prokaryotes that have applications to human health and numerous biological activities as dietary supplements. Cyanobacteria produce biologically active and chemically diverse compounds such as cyclic peptides, lipopeptides, fatty acid amides, alkaloids, and saccharides. More than 50% of marine cyanobacteria are potentially exploitable for the extraction of bioactive substances, which are effective in killing cancer cells by inducing apoptotic death. The current review emphasizes that not even 10% of microalgal bioactive components have reached commercialized platforms due to difficulties related to solubility. Considering these factors, they should be considered as a potential source of natural products for drug discovery and drug delivery approaches. Nanoformulations employing a wide variety of nanoparticles and their polymerized forms could be an emerging approach to the development of new cancer drugs. This review highlights recent research on microalgae-based medicines or compounds as well as their biomedical applications. This review further discusses the facts, limitations, and commercial market trends related to the use of microalgae for industrial and medicinal purposes.

Indexed as

Antineoplastic AgentsBiological FactorsBiotechnologyCommerceCyanobacteriaDrug CompoundingDrug Delivery SystemsDrug DiscoveryDrug StabilityHumansMicroalgaeNanoparticlesNanotechnologyNeoplasmsSolubilityAntineoplastic AgentsBiological Factorscommercial drawbacksdrug developmentmicroalgae/cyanobacteriananoformulation

Identifiers

PMID29882898
PMCPMC6024944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.