Evidence map›Paper›PMID 29882884›Full record

Trial reportNutrients2018

The Effect of Low-Carbohydrate Diet on Glycemic Control in Patients with Type 2 Diabetes Mellitus.

Li-Li Wang, Qi Wang, Yong Hong, Omorogieva Ojo, Qing Jiang, Yun-Ying Hou, Yu-Hua Huang, Xiao-Hua Wang

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05579561 (Is the Vegetarian Version of Therapeutic Carbohydrate Restriction as Effective as the Omnivore Version), which is not on this map. Cited by 69 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05579561 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Is the Vegetarian Version of Therapeutic Carbohydrate Restriction as Effective as the Omnivore Version: In the Context of Remission of Type 2 Diabetes

TypeinterventionalSponsorBloomedInRan2022 to 2023Enrolled19ConditionsDiabetes Mellitus Type 2 in Obese, Hypertension, Diabetes Mellitus Type 2 With Hyperglycemia, InflammationArmsDiet
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li-Li WangSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. wanglili83476@suda.edu.cn.
Qi WangSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. xuweipan@whu.edu.cn.
Yong HongSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. 20175231003@stu.suda.edu.cn.
Omorogieva OjoDepartment of Adult Nursing and Paramedic Science, University of Greenwich, London SE9 2UG, UK. o.ojo@greenwich.ac.uk.ORCID 0000-0003-0071-3652
Qing JiangSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. jiangqing2015@suda.edu.cn.
Yun-Ying HouSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. houyunying@suda.edu.cn.
Yu-Hua HuangMedical College, Soochow University, Suzhou 215006, China. Huangyuhua@suda.edu.cn.
Xiao-Hua WangSchool of Nursing, Medical College, Soochow University, Suzhou 215006, China. wangxiaohua@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn China, a low-fat diet (LFD) is mainly recommended to help improve blood glucose levels in patients with type 2 diabetes mellitus (T2DM). However, a low-carbohydrate diet (LCD) has been shown to be effective in improving blood glucose levels in America and England. A few studies, primarily randomized controlled trials, have been reported in China as well.

methodFirstly, we designed two 'six-point formula' methods, which met the requirements of LCD and LFD, respectively. Fifty-six T2DM patients were recruited and randomly allocated to the LCD group (

resultsForty-nine patients completed the study. The proportions of calories from three macronutrients the patients consumed met the requirements of LCD and LFD. Compared to the LFD group, there was a greater decrease in HbA1c level in the LCD group (-0.63% vs. -0.31%,

conclusionsLCD can improve blood glucose more than LFD in Chinese patients with T2DM. It can also regulate blood lipid, reduce BMI, and decrease insulin dose in patients with T2DM. In addition, the six-point formula is feasible, easily operable, and a practical educational diet for Chinese patients with T2DM.

Indexed as

Diet, Carbohydrate-RestrictedDiet, DiabeticDiet, Fat-RestrictedAgedBiomarkersBlood GlucoseBody Mass IndexChinaCholesterolDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinMaleBiomarkersBlood GlucoseCholesterolGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic AgentsInsulinblood glucosecarbohydratediabetes mellitusdietfasting blood glucoseHbA1cpostprandial blood glucose

Identifiers

PMID29882884
PMCPMC6024764

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.