Evidence map›Paper›PMID 29882848›Full record

ArticleMarine drugs2018

Structural Elucidation of Irish Organic Farmed Salmon (Salmo salar) Polar Lipids with Antithrombotic Activities.

Alexandros Tsoupras, Ronan Lordan, Martina Demuru, Katie Shiels, Sushanta Kumar Saha, Constantina Nasopoulou, Ioannis Zabetakis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03603769 (In Vitro And Ex Vivo Anti-Inflammatory Activities Of Salmon Polar Lipids), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03603769 nacompletednot on this map

In Vitro And Ex Vivo Anti-Inflammatory Activities Of Salmon Polar Lipids

TypeinterventionalSponsorUniversity of LimerickRan2018 to 2019Enrolled6ConditionsCardiovascular DiseasesArmsFood supplement capsules containing Salmon-Polar Lipids, Placebo food supplement capsule
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 48 citations in OpenAlex.

  1. Review
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  4. Review
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  6. Review
  7. Article
  8. Article
  9. Article
  10. Marine Natural Products and Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021
    Review
  11. Article
  12. Marine Antithrombotics.Marine drugs · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Alexandros TsouprasDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland. Alexandros.Tsoupras@ul.ie.
Ronan LordanDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland. Ronan.Lordan@ul.ie.ORCID 0000-0001-9668-3368
Martina DemuruDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland. marti.demuru@hotmail.it.
Katie ShielsShannon Applied Biotechnology Centre, Limerick Institute of Technology, Moylish Park, V94 E8YF Limerick, Ireland. Katie.Shiels@lit.ie.
Sushanta Kumar SahaShannon Applied Biotechnology Centre, Limerick Institute of Technology, Moylish Park, V94 E8YF Limerick, Ireland. Sushanta.Saha@lit.ie.ORCID 0000-0002-3981-8833
Constantina NasopoulouDepartment of Food Science and Nutrition, School of the Environment, University of the Aegean, GR 81400 Myrina, Lemnos, Greece. knasopoulou@aegean.gr.ORCID 0000-0003-1854-9117
Ioannis ZabetakisDepartment of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland. Ioannis.Zabetakis@ul.ie.ORCID 0000-0001-8175-950X
University of Limerick · IEShannon Applied Biotechnology Centre · IEUniversity of Cagliari · ITUniversity of the Aegean · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While several marine polar lipids (PL) have exhibited cardioprotective properties through their effects on the platelet-activating factor (PAF) pathways, salmon PL have not been tested so far. In this study, the antithrombotic activities of salmon PL were assessed in human platelets and the structural characterisation of bioactive salmon PL was performed by GC-MS and LC-MS analyses. PL from fillets of Irish organic farmed salmon (

Indexed as

Salmo salarAnimalsChemical FractionationChromatography, Thin LayerFibrinolytic AgentsFisheriesGas Chromatography-Mass SpectrometryHumansInhibitory Concentration 50IrelandLipidsPlatelet Activating FactorPlatelet AggregationSignal TransductionStructure-Activity RelationshipFibrinolytic AgentsLipidsPlatelet Activating Factorantithromboticdocosahexaenoic acid (DHA)GC-MSLC-MSphosphatidylcholinephosphatidylethanolamineplatelet-activating factor (PAF)platelet aggregationpolar lipidspolyunsaturated fatty acids (PUFA)salmonthrombin

Identifiers

PMID29882848
PMCPMC6025065
OpenAlexW2804819411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.