Evidence map›Paper›PMID 29882774›Full record

ArticleInternational journal of molecular sciences2018

Influence of Bacterial Biofilm Polysaccharide Structure on Interactions with Antimicrobial Peptides: A Study on

Barbara Bellich, Cristina Lagatolla, Alessandro Tossi, Monica Benincasa, Paola Cescutti, Roberto Rizzo

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Relationship between biofilm formation and antibiotic resistance ofFrontiers in cellular and infection microbiology · 2024
    Review
  8. Alterations in Antibiotic Susceptibility ofInternational journal of molecular sciences · 2023
    Article
  9. Phenotypic Traits and Probiotic Functions ofFoods (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Defining principles that influence antimicrobial peptide activity against capsulatedProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  15. Article
  16. Targeting the Sugary Armor ofFrontiers in cellular and infection microbiology · 2019
    Review
  17. Classification of Clinical Isolates ofFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Barbara BellichDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. bbellich@units.it.ORCID 0000-0002-5257-6584
Cristina LagatollaDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. clagatolla@units.it.ORCID 0000-0001-5739-6761
Alessandro TossiDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. atossi@units.it.
Monica BenincasaDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. mbenincasa@units.it.
Paola CescuttiDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. pcescutti@units.it.
Roberto RizzoDepartment of Life Sciences, University of Trieste, Via Licio Giorgieri 1, 34127 Trieste, Italy. rizzor@units.it.ORCID 0000-0002-9809-592X
University of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balneotherapy is a clinically effective complementary approach in the treatment of low-grade inflammation- and stress-related pathologies. The biological mechanisms by which immersion in mineral-medicinal water and the application of mud alleviate symptoms of several pathologies are still not completely understood, but it is known that neuroendocrine and immunological responses—including both humoral and cell-mediated immunity—to balneotherapy are involved in these mechanisms of effectiveness; leading to anti-inflammatory, analgesic, antioxidant, chondroprotective, and anabolic effects together with neuroendocrine-immune regulation in different conditions. Hormesis can play a critical role in all these biological effects and mechanisms of effectiveness. The hormetic effects of balneotherapy can be related to non-specific factors such as heat—which induces the heat shock response, and therefore the synthesis and release of heat shock proteins—and also to specific biochemical components such as hydrogen sulfide (H₂S) in sulfurous water and radon in radioactive water. Results from several investigations suggest that the beneficial effects of balneotherapy and hydrotherapy are consistent with the concept of hormesis, and thus support a role for hormesis in hydrothermal treatments.

Indexed as

AnimalsAnti-Bacterial AgentsBiofilmsCathelicidinsCattleEscherichia coliEscherichia coli InfectionsKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsPolysaccharides, BacterialAnti-Bacterial AgentsCathelicidinsPolysaccharides, Bacterialantimicrobial peptidesbacterial biofilmbacterial protectionexopolysaccharides biological activitymatrix exopolysaccharides

Identifiers

PMID29882774
PMCPMC6032227
OpenAlexW2807145793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.